Publication date: Available online 18 June 2020Source: Hearing ResearchAuthor(s): Xingle Zhao, Chenxi Jin, Tingting Dong, Zhuoer Sun, Xiaofei Zheng, Baoyi Feng, Zhenzhe Cheng, Xiang Li, Yong Tao, Hao Wu
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Abstract The aim of this study was to examine the effects of 5 days of anodal-transcranial direct current stimulation (a-tDCS) over the primary motor cortex (M1) on lower extremity functional performance in healthy elderly people. This was a randomized, double-blinded, sham-controlled study whereby 32 healthy older individuals participated in two groups. The intervention group received 20 min of a-tDCS (1 mA) over the M1 on five consecutive days. The sham group received the same...
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Publication date: Available online 17 June 2020Source: Journal of Neuroscience MethodsAuthor(s): Jai J. Suckley, Timothy J. Waters, Michael Tran, Paul J. Stapley, Jonathan Shemmell, Joel A. Walsh, Darryl J. Mcandrew
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New insights into the anatomy of the inner ear of prehistoric reptiles, the thalattosuchians, revealed details about the evolutionary adaption during the transition into the ocean after a long semiaquatic phase. These new findings were made possible by the use of a Canon high-tech computed tomography (CT) scanner.
When choosing a mate, females of different subspecies of Drosophila mojavensis recognize the right mating partners either mainly by their song or by their smell. New species apparently evolve when the chemical mating signal is altered and when, in turn, the signal is reinterpreted by the opposite sex in the context of other signals, such as the courtship song.
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Publication date: Available online 18 June 2020Source: European Journal of Surgical OncologyAuthor(s): Tomohiro Fujiwara, Jonathan Stevenson, Michael Parry, Yusuke Tsuda, Yoichi Kaneuchi, Lee Jeys
Publication date: Available online 18 June 2020Source: European Journal of Surgical OncologyAuthor(s): Isabel T. Rubio, Roberto Rodriguez-Revuelto, Martin Espinosa-Bravo, Christian Siso, Joaquin Rivero, Antonio Esgueva
Publication date: Available online 17 June 2020Source: European Journal of Surgical OncologyAuthor(s): Jae-Seung Chung, Sung Kyu Hong, Sang Chul Lee, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, Sung Hoo Hong, Yong June Kim, Seok Ho Kang, Jinsoo Chung, Tae Gyun Kwon, Eu Chang Hwang, Seok-Soo Byun
Publication date: Available online 17 June 2020Source: European Journal of Surgical OncologyAuthor(s): Savio G. Barreto, Jorg Kleeff
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Publication date: Available online 17 June 2020Source: Gait & PostureAuthor(s): Adam Goodworth, Amy Kratzer, Sandy Saavedra
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Medtronic won the EU CE Mark for its MiniMed 780G closed loop insulin pump that features both Medtronic’s own SmartGuard algorithm and MD-Logic, an algorithm developed by DreaMed Diabetes, a small Israeli firm. The system, indicated to be used by patients with type 1 diabetes between ages 7 and 80, automatically delivers both basal insulin and correcting boluses every five minutes, if necessary. Such close monitoring and control of blood glucose levels may help patients stay within...
Scientists at Purdue University are reporting a skin patch that can deliver chemotherapy into melanoma tumors in an effective, convenient, and painless way. This may be an important development, as currently chemotherapy delivery options are limited and result in systemic exposure in the whole body and/or poor effectiveness. Previous attempts at chemotherapy delivery via a patch required the use of large needles, which themselves dissolved way too fast once inside the skin to maintain...
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Publication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Rafael Zúñiga, Guierdy Concha, Angel Cayo, Rocio Cikutović-Molina, Bárbara Arevalo, Wendy González, Marcelo A. Catalán, Leandro Zúñiga
Publication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Qi You, Yuan Yao, Jinyu Wu, Congcong Cheng, Yunxiu Li, Haitao Yuan
Publication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Bailin He, Qiang Wang, Xiaoli Liu, Ziyuan Lu, Jiaochan Han, Chengyun Pan, Bing Z. Carter, Qifa Liu, Na Xu, Hongsheng Zhou
Publication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Baiqi Wang, Lili Xu, Ju Zhang, Xinru Cheng, Qianya Xu, Jian Wang, Fengxia Mao
Publication date: September 2020Source: Biomedicine & Pharmacotherapy, Volume 129Author(s): Ling Fu, Lingling Zhou, Shan Geng, Ming Li, Wei Lu, Yan Lu, Zhe Feng, Xueping Zhou
Publication date: August 2020Source: Biomedicine & Pharmacotherapy, Volume 128Author(s): Lili Zhang, Jun Li, Li Cui, Jinchun Shang, Fen Tian, Rong Wang, Guangqun Xing
Publication date: August 2020Source: Biomedicine & Pharmacotherapy, Volume 128Author(s): Xian-Feng Zhang, Yang Yang, Xin-Yu Yang, Qian Tong
Publication date: August 2020Source: Biomedicine & Pharmacotherapy, Volume 128Author(s): Li Zhu, Xiuping Liu, Dongmei Li, Shuhong Sun, Yue Wang, Xianghong Sun
Publication date: August 2020Source: Biomedicine & Pharmacotherapy, Volume 128Author(s): Zihong Zhang, Hui Liu, Zhe Zhao, Caixia Zang, Cheng Ju, Fangyuan Li, Lu Wang, Hanyu Yang, Xiuqi Bao, Yang Yu, Xinsheng Yao, Dan Zhang
Publication date: August 2020Source: Biomedicine & Pharmacotherapy, Volume 128Author(s): Chunyue Yu, Zeqi Su, Yicong Li, Yadong Li, Kaige Liu, Fuhao Chu, Ting Liu, Runhua Chen, Xia Ding
Publication date: August 2020Source: Biomedicine & Pharmacotherapy, Volume 128Author(s): Jing Wang, Bing Wang, Ling-Qiang Chen, Jin Yang, Zhi-Qiang Gong, Xue-Ling Zhao, Chun-Qiang Zhang, Kai-Li Du
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Abstract Recent studies suggest a causal link of childhood leukemia and brain tumor with repeated computed tomography (CT) scans. The reasons why frequent CT scans are taken in a specific child remain unclear. The present study aimed to clarify the medical reasons why frequent CT examinations in children, and the characteristics of the diseases of those children that required multiple CT scans. A long-term follow-up retrospective study was conducted over a 12.75-year period at...
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Related Articlesovel Polymeric Lotion Formulation of Once-Daily Tazarotene (0.045%) for Moderate-to-Severe Acne: Pooled Phase 3 Analysis. J Drugs Dermatol. 2020 Mar 01;19(3):272-279 Authors: Tanghetti EA, Werschler WP, Lain E, Guenin E, Harris S, Loncaric A, Pillai R Abstract Background: As current tazarotene formulations indicated for acne (0.1%) can cause irritation, a new tazarotene 0.045% lotion formu-lation was developed using polymeric emulsion...
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Related ArticlesGrowth Factor Signaling Regulates Mechanical Nociception in Flies and Vertebrates. J Neurosci. 2019 07 24;39(30):6012-6030 Authors: Lopez-Bellido R, Puig S, Huang PJ, Tsai CR, Turner HN, Galko MJ, Gutstein HB Abstract Mechanical sensitization is one of the most difficult clinical pain problems to treat. However, the molecular and genetic bases of mechanical nociception are unclear. Here we develop a Drosophila model of mechanical nociception...
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Abstract Eosinophilic otitis media (EOM) is an inflammatory chronic disease of the middle ear, characterized by the presence of a particularly viscous effusion with a high content of protein toxins of eosinophilic origin in the middle ear cavity. The pathology has relationship with bronchial asthma, allergic rhinitis and chronic rhinosinusitis with nasal polyps. EOM is characterized by a sluggish course, a tendency to relapse, which can lead to a gradual hearing decrease up to...
Abstract Thyroid cancer has a good prognosis among all cancers, the disease being confined to the thyroid gland for a long time. Thyroid cancer with the direct invasion of internal jugular vein and SCM muscle is a rare condition. In carcinoma thyroid, extensive vascular invasion is considered as a risk factor for distant metastasis and early relapse. We report a case of carcinoma thyroid with internal jugular vein tumor thrombosis and sternocleidomastoid muscle invasion with review...
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Related ArticlesSex, Drugs, and Impulse Regulation: A Perspective on Reducing Transmission Risk Behavior and Improving Mental Health Among MSM Living With HIV. Front Psychol. 2020;11:1005 Authors: Arends RM, van den Heuvel TJ, Foeken-Verwoert EGJ, Grintjes KJT, Keizer HJG, Schene AH, van der Ven AJAM, Schellekens AFA Abstract Unprotected sexual contact continues to be a main cause of HIV transmission and poses certain key populations at increased risk...
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Publication date: Available online 17 June 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Benjamin Fournier, Maud Tusseau, Marine Villard, Christophe Malcus, Emilie Chopin, Emmanuel Martin, Debora Jorge Cordeiro, Nicole Fabien, Mathieu Fusaro, Alexandra Gauthier, Nathalie Garnier, David Goncalves, Sonia Lounis, Christelle Lenoir, Anne-Laure Mathieu, Marion Moreews, Magali Perret, Capucine Picard, Cécile Picard, Françoise Poitevin
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This survey study of patients with coronavirus disease 2019 investigates the presence of sinonasal manifestations at the onset of the disease to achieve an earlier diagnosis.
This cross-sectional study surveys the websites of 16 leading hearing aid brands for claims that using hearing aids can forestall or prevent dementia.
This case-control study examines the association between multimodal analgesia administration and perioperative opioid requirements in patients undergoing head and neck surgery with free flap reconstruction and investigates whether multimodal analgesia alters the duration of stay in the postanesthesia care unit.
This case report describes a woman in her 60s with a previous history of basal cell carcinoma who presented with multiple wart-like lesions that erupted on both her cheeks 2 weeks after full-face fractional CO2 laser resurfacing.
In the article titled “Severe Facial-Disfiguring Xeroderma Pigmentosum With Rapidly Progressing Malignant Tumors,” published in the February 2019 issue of JAMA Otolaryngology–Head & Neck Surgery, indication of co–first authorship was missing. Authors Tao Zan, MD, PhD, and Xin Huang, MD, are co–first authors of this article. The article has been corrected online.
This Viewpoint describes techniques by which otolaryngologic physical examination can be performed when the patient is not physically present with the examiner.
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In Reply We appreciate Chen and Han’s interest in our study. In their letter, they acknowledge the equal gender representation present in our study sample. All residents in the Department of Otolaryngology at our tertiary academic center were invited to participate in this study. Therefore, this was a fortunate circumstance, largely resulting from the relative gender balance in our residency program. We agree with Chen and Han that women are often found in the literature to be more burdened by burnout...
In Reply We appreciate the comments from Chen and Liang regarding our recent article. Our blinded, prospective study sought to objectively define the association of endotracheal intubation with laryngeal function.
This quality improvement study uses tumor size to assess which patients are at low risk for papillary thyroid cancer and may be candidates for active surveillance as a treatment strategy.
This Special Communication provides safety recommendations for health care workers regarding otolaryngologic examinations and surgical procedures during the coronavirus disease 2019 (COVID-19) pandemic.
This Patient Page describes the prevalence and risks of thyroid nodules.
Mission Statement: JAMA Otolaryngology–Head & Neck Surgery provides timely information for physicians and scientists concerned with diseases of the head and neck. Given the diversity of structure and function based in this anatomic region, JAMA Otolaryngology–Head & Neck Surgery publishes clinical, translational, and population health research from an array of disciplines. We place a high priority on strong study designs that accurately identify etiologies, evaluate diagnostic strategies,...
This case series analyzes the differences in presentation of voice and laryngeal disorders in patients with fibromyalgia, irritable bowel syndrome, and/or chronic fatigue syndrome.
This cohort study assesses whether continuous positive airway pressure (CPAP) therapy is associated with nasal congestion in patients with allergic rhinitis, nonallergic rhinitis, or no rhinitis.
This cohort study of individuals with and without burning mouth syndrome uses data from the Korean National Health Insurance Service to examine the association between burning mouth syndrome and the risk of developing psychoneurological conditions among patients with burning mouth syndrome.
To the Editor We congratulate Last et al for their valuable contribution to our understanding of the risk of contralateral nodal spread in patients with human papillomavirus (HPV)–associated squamous cell carcinoma of the base of the tongue. They report occult contralateral nodal involvement in 21.4% of the cohort and appropriately argue that this warrants bilateral neck management in patients with this disease. We have 2 questions that would be relevant to the head and neck oncology community.
Functional laryngeal and airway disorders are characterized by apparently normal anatomy and neurological function accompanied by clinically significant symptoms, which can include dysphonia, dysphagia, globus sensation, and dyspnea. These disorders are often diagnoses of exclusion, since the presenting symptoms can also accompany important anatomic and neurologic abnormalities that must be ruled out. Primary muscle tension dysphonia (MTD), also often called functional dysphonia or hyperfunctional...
It is an exciting time in human spaceflight, with the advent of commercial spaceflight and the new Artemis Program to return astronauts to the moon. Although it has been 50 years since the Apollo 11 moon landing and 20 years since humans began continuously residing on the International Space Station (ISS), researchers continue to make novel discoveries regarding the human body in space. In this issue of JAMA Otolaryngology–Head & Neck Surgery, Inglesby et al report on magnetic resonance imaging...
In this issue of JAMA Otolaryngology–Head & Neck Surgery, J.-Y. Kim et al report a population-based study using the Korean National Health Insurance Service–National Sample Cohort database that collected data on a large nationwide cohort. The main aim of the study was to investigate the incidence of psychopathological (anxiety and depression) and neurological (dementia and Parkinson disease) conditions in patients with a clinical diagnosis of burning mouth syndrome (patient group) who were matched...
This cohort study assesses whether increased duration of bolster use is associated with increased split-thickness skin graft uptake rates following fibula free flap reconstruction surgery.
There is a new tradition in the otolaryngology publishing community that, to our knowledge, is unique to our specialty. Editors-in-chief of otolaryngology journals in the United States, and intermittently some of our international colleagues such as the editor of the Journal of Laryngology & Otology in England, sit down together twice a year to discuss topics of mutual interest, maintain lines of communication and friendships, and share perspectives on the evolution of otolaryngology–head and...
To the Editor We thank Stevens et al for their study analyzing the association of weekly protected nonclinical time with prevalence of burnout and general well-being in a sample of otolaryngology resident physicians. In the study, the intervention was alternated with the control (no weekly protected clinical time) at 6-week intervals; during which resident physicians had to complete questionnaires that sought to assess burnout, depression, fatigue, and anxiety. They reported that 2 hours of weekly...
This cross-sectional study estimates the association between hearing loss and postural instability in Korean adults 40 years and older and presents criteria for identifying the hearing loss group at risk for developing concurrent postural instability.
This Viewpoint highlights important perioperative considerations when planning for open tracheostomy in an infected patient during the COVID-19 pandemic.
In Reply Thank you for sharing with us Dr Parham’s letter to the editor regarding our recent publication, “Complications, Mortality, and Functional Decline in Patients 80 Years or Older Undergoing Major Head and Neck Ablation and Reconstruction.” We are appreciative of the comments in the letter and agree with Dr Parham’s assertion that cognitive functional decline and postoperative delirium are common and major complications in this vulnerable population. The objective of the study was to combine...
In Reply We thank Stokes et al for their interest in our article regarding contralateral nodal metastases in patients with human papillomavirus–related base of tongue carcinoma. Their first question relates to how we can clinically identify patients with nodal metastases using positron emission tomographic (PET) imaging. In our study, 53 of the 70 patients (76%) with no clinically evident contralateral nodal disease had PET or PET/computed tomographic (CT) images available for review. Of the 15 patients...
To the Editor I am writing to compliment Fancy et al on their article addressing complications, mortality, and functional decline in patients aged 80 years or older undergoing major head and neck ablation and reconstruction. This article addressed a void in the literature that has a significant effect on perioperative surgical planning and patient and caregiver counseling. In agreement with a growing body of surgical literature, the authors found that the old old are a vulnerable surgical population...
This cohort study examines preflight to postflight changes in the opacification of the paranasal sinuses and mastoid air cells in Space Shuttle astronauts and International Space Station astronauts and determines whether there are differences between the 2 groups.
In this issue of JAMA Otolaryngology–Head & Neck Surgery, Bang et al report a large, population-based study using data from the Korea National Health and Nutrition Examination Survey V. In this survey, 3864 adults (40 years and older) underwent a hearing test and a balance test. Hearing was measured on both sides via pure tone average and was classified according to the World Health Organization categories for normal, mild, or moderate hearing loss. Static balance was measured by the ability...
To the Editor We thank Campbell et al for their study analyzing the association of potential clinical factors with the development of unilateral vocal fold immobility (UVFI) following prolonged (>12 hours) mechanical ventilation. In their study, they report a UVFI incidence rate of 7% and established an association between inpatient hypotension, preadmission vascular disease, coronary artery disease, and use of vasopressors with development of UVFI.
This systematic review and meta-analysis assesses whether age is associated with progression of low-risk papillary thyroid carcinoma (tumor growth or incident metastatic disease) in adults under active surveillance.
This Viewpoint describes the precautions taken when treating patients in Hong Kong since the novel coronavirus disease 2019 (COVID-19) epidemic began in China.
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