Related ArticlesCholecysto-Hydatid Cyst Fistula: A Rare Cause of Cholangitis. Am J Case Rep. 2020 Jun 17;21:e921914 Authors: Bilgi Kırmacı M, Akay T, Özgül E, Yılmaz S Abstract BACKGROUND Cholecysto-hydatid fistula is a rare complication of liver echinococcosis; suppurative cholangitis due to cholecysto-hydatid fistula is even rarer. A multidisciplinary approach is required by radiology and surgery departments during the preoperative diagnosis and treatment...
Thu Jun 18, 2020 13:44
Related ArticlesPrimary Biatrial Cardiac Rhabdomyosarcoma. Braz J Cardiovasc Surg. 2020 Jun 01;35(3):399-401 Authors: Uchida T, Kuroda Y, Sadahiro M Abstract Primary malignant neoplasms of the heart are rare. Cardiac rhabdomyosarcoma is the second most common primary sarcoma. We report a rare case of a 49-year-old woman with a huge biatrial cardiac rhabdomyosarcoma treated by performing surgical resection followed by salvage chemotherapy for local recurrence....
Thu Jun 18, 2020 14:44
Related ArticlesRare Presentation of Benign Osteochondroma: A Case Report. J Orthop Case Rep. 2020;9(6):82-85 Authors: Ratra R, Peshin C Abstract Introduction: Osteochondromas are the most common benign bone tumors (accounting for 20-50% of all benign bone tumors). They are developmental malformations rather than true neoplasms and are thought to originate within the periosteum. They usually affect bones that develop by enchondral ossification and rarely...
Thu Jun 18, 2020 13:41
Related ArticlesParathyroid Adenoma as a Rare Cause of Persistent Hypercalcemia in a Female with Polycythemia Vera. Case Rep Oncol. 2020 May-Aug;13(2):578-582 Authors: Abdalhadi AM, Yassin MA Abstract Polycythemia vera is one of the myeloproliferative neoplasms that is distinguished by the uncontrolled production of blood cells and an increased red cell mass due to acquired JAK2 mutation. It has many complications and it might increase the risk of other...
Thu Jun 18, 2020 13:41
Related ArticlesPleomorphic Leiomyosarcoma of the Adrenal Gland in a Young Woman: A Case Report and Review of the Literature. Onco Targets Ther. 2020;13:4705-4713 Authors: Wang Y, Teng Y, Na S, Yuan Y Abstract Leiomyosarcoma usually arises in the uterus, abdominal and urologic viscera, and walls of large and small blood vessels. However, primary adrenal leiomyosarcoma is extremely rare with only 39 cases previously reported in English-language literature....
Thu Jun 18, 2020 13:41
Related ArticlesIdentification of Altered Genes in Gallbladder Cancer as Potential Driver Mutations for Diagnostic and Prognostic Purposes: A Computational Approach. Cancer Inform. 2020;19:1176935120922154 Authors: D'Afonseca V, Arencibia AD, Echeverría-Vega A, Cerpa L, Cayún JP, Varela NM, Salazar M, Quiñones LA Abstract Prognostic markers for cancer can assist in the evaluation of survival probability of patients and help clinicians to assess the available...
Thu Jun 18, 2020 13:41
Related ArticlesChemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors. Commun Biol. 2020 Jun 16;3(1):310 Authors: Savage P, Pacis A, Kuasne H, Liu L, Lai D, Wan A, Dankner M, Martinez C, Muñoz-Ramos V, Pilon V, Monast A, Zhao H, Souleimanova M, Annis MG, Aguilar-Mahecha A, Lafleur J, Bertos NR, Asselah J, Bouganim N, Petrecca K, Siegel PM, Omeroglu A, Shah SP, Aparicio S, Basik M, Meterissian...
Thu Jun 18, 2020 13:41
Related ArticlesSETD1B-associated neurodevelopmental disorder. J Med Genet. 2020 Jun 16;: Authors: Roston A, Evans D, Gill H, McKinnon M, Isidor B, Cogné B, Mwenifumbo J, van Karnebeek C, An J, Jones SJM, Farrer M, Demos M, Connolly M, Gibson WT, CAUSES Study, EPGEN Study Abstract BACKGROUND: Dysfunction of histone methyltransferases and chromatin modifiers has been implicated in complex neurodevelopmental syndromes and cancers. SETD1B encodes a lysine-specific...
Thu Jun 18, 2020 13:41
Related ArticlesManagement of Drug Resistance in Mantle Cell Lymphoma. Cancers (Basel). 2020 Jun 12;12(6): Authors: Roué G, Sola B Abstract Mantle cell lymphoma (MCL) is a rare but aggressive B-cell hemopathy characterized by the translocation t(11;14)(q13;q32) that leads to the overexpression of the cell cycle regulatory protein cyclin D1. This translocation is the initial event of the lymphomagenesis, but tumor cells can acquire additional alterations...
Thu Jun 18, 2020 13:41
Related ArticlesEpidemiology of Signet Ring Cell Adenocarcinomas. Cancers (Basel). 2020 Jun 11;12(6): Authors: Benesch MGK, Mathieson A Abstract Signet ring cell adenocarcinomas (SRCCs) are a rare histological subtype of adenocarcinomas with a poor prognosis, typically due to advanced disease at diagnosis. A signet ring cell, mimicking its moniker, contains abundant intracytoplasmic mucin that pushes the nucleus to the periphery. In these cancers, this...
Thu Jun 18, 2020 13:41
Related ArticlesNICE guideline for rectal cancer: already out of date. Lancet. 2020 06 13;395(10240):e105-e106 Authors: Glynne-Jones R, Harrison M, Cheetham D PMID: 32534652 [PubMed - indexed for MEDLINE]
Thu Jun 18, 2020 13:41
Related ArticlesPure abscopal effect of radiotherapy in a salivary gland carcinoma: Case report, literature review, and a search for new approaches. Cancer Radiother. 2020 Jun;24(3):226-246 Authors: Ellerin BE, Demandante CGN, Martins JT Abstract We report the case of an 84-year-old woman with poorly differentiated non-small cell carcinoma of the right parotid who presented with headache, was found to have a primary right parotid gland cancer as well...
Thu Jun 18, 2020 13:41
Related ArticlesHigh-purity isolation of rare single cells from blood using a tiered microchip system. PLoS One. 2020;15(3):e0229949 Authors: Gur O, Chang CL, Jain R, Zhong Y, Savran CA Abstract We present a two-tiered microchip system to capture and retrieve rare cells from blood samples with high purity. The first module of the system is a high throughput microfluidic interface that is used to immunomagnetically isolate targeted rare cells from whole...
Thu Jun 18, 2020 13:41
Related ArticlesAdenoid cystic carcinoma of the palate with isolated cutaneous metastasis: a unique case and review of current and future treatment modalities of metastatic disease. Int J Oral Maxillofac Surg. 2020 Jun;49(6):700-708 Authors: Armstrong LTD, Subramaniam SS, Borgna S Abstract Adenoid cystic carcinoma (ACC) is an aggressive salivary gland neoplasm characterized by high rates of local recurrence, early metastasis, and a poor long-term prognosis....
Thu Jun 18, 2020 13:41
Related ArticlesParaneoplastic pyoderma gangrenosum associated with adenocarcinoma of the rectosigmoid junction: a case report. J Med Case Rep. 2019 Dec 07;13(1):372 Authors: Alassani F, Kassang P, Amouzou EG, Tchangai B, Sakiye KA, Darré T, Saka B, Attipou K Abstract INTRODUCTION: Pyoderma gangrenosum is a rare, idiopathic, inflammatory, neutrophilic dermatitis characterized by sterile skin ulceration. It can be associated with an underlying pathology,...
Thu Jun 18, 2020 13:41
Related Articles2019 international clinical practice guidelines for the treatment of venous thromboembolism - Authors' reply. Lancet Oncol. 2019 12;20(12):e656 Authors: Douketis JD, Frere C, Farge D, International Thrombosis and Cancer Initiative members PMID: 31797782 [PubMed - indexed for MEDLINE]
Thu Jun 18, 2020 13:41
Related ArticlesLymphocytic ganglionitis leading to megacolon in lymphocyte-rich glioblastoma. J Neuroimmunol. 2019 12 15;337:577075 Authors: Ahrendsen JT, Anderson KR, Anderson MP Abstract T-cell immune attack of cancer cells underlies the efficacy of immune checkpoint inhibitors in many cancer subtypes, but is not yet well established in the primary brain cancer glioblastoma. Immune checkpoint inhibitor treatments that disinhibit the immune system...
Thu Jun 18, 2020 13:41
Related ArticlesDural Extranodal Marginal Zone Lymphoma in an XRCC2 Mutation Carrier. J Neuropathol Exp Neurol. 2019 12 01;78(12):1174-1177 Authors: Gvozdjan K, Zacharia BE, Bayerl MG, Tomi-Olugbodi A, Boyer C, Specht CS Abstract Dural extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a rare entity without an associated recurrent genetic abnormality. Only one case has been described in a woman with history of...
Thu Jun 18, 2020 13:41
Related ArticlesCommon Secondary Genomic Variants Associated With Advanced Epithelioid Hemangioendothelioma. JAMA Netw Open. 2019 10 02;2(10):e1912416 Authors: Seligson ND, Awasthi A, Millis SZ, Turpin BK, Meyer CF, Grand'Maison A, Liebner DA, Hays JL, Chen JL Abstract Importance: Epithelioid hemangioendothelioma (EHE) is a rare, malignant vascular sarcoma characterized in most cases by a WWTR1-CAMTA1 fusion. The clinical course of EHE exhibits a dual...
Thu Jun 18, 2020 13:41
Related ArticlesMyxopapillary ependymoma of cauda equina presented with communicating hydrocephalus and papilloedema: A case report. Med J Malaysia. 2019 08;74(4):338-340 Authors: Ting SL, Jobli AT, Sim SK, Norlida Awang Ojep DK Abstract We reported a case of cauda equina myxopapillary ependymoma in a patient who presented with atypical history of progressive blurring of vision. Ophthalmology examination revealed relative afferent pupillary defect, binasal...
Thu Jun 18, 2020 13:41
Related ArticlesPOEMS syndrome: A rare paraneoplastic presentation of spinal plasmacytoma. Med J Malaysia. 2019 08;74(4):335-337 Authors: Low JM, Basiam S, Ahlam Naila K Abstract The acronym POEMS syndrome was coined for a unique multisystem disorder characterised by peripheral neuropathy, organomegaly, endocrinopathies, monoclonal gammopathy and skin changes. We report a male patient presenting to us with spinal plasmacytoma complicated with paraplegia....
Thu Jun 18, 2020 13:41
Related ArticlesAnalysis of the Genomic Landscape in ALK+ NSCLC Patients Identifies Novel Aberrations Associated with Clinical Outcomes. Mol Cancer Ther. 2019 09;18(9):1628-1636 Authors: Couëtoux du Tertre M, Marques M, Tremblay L, Bouchard N, Diaconescu R, Blais N, Couture C, Pelsser V, Wang H, Higenell V, Izzi L, Gambaro K, Hoffert C, Srivastava A, Spatz A, Rousseau C, McNamara S, Cohen V, Batist G, Agulnik J Abstract Rearrangements in the anaplastic...
Thu Jun 18, 2020 13:41
Related ArticlesCabozantinib in advanced non-clear-cell renal cell carcinoma: a multicentre, retrospective, cohort study. Lancet Oncol. 2019 04;20(4):581-590 Authors: Martínez Chanzá N, Xie W, Asim Bilen M, Dzimitrowicz H, Burkart J, Geynisman DM, Balakrishnan A, Bowman IA, Jain R, Stadler W, Zakharia Y, Narayan V, Beuselinck B, McKay RR, Tripathi A, Pachynski R, Hahn AW, Hsu J, Shah SA, Lam ET, Rose TL, Mega AE, Vogelzang N, Harrison MR, Mortazavi A, Plimack ER, Vaishampayan...
Thu Jun 18, 2020 13:41
Related ArticlesShort-Term Ultramicronized Palmitoylethanolamide Therapy in Patients with Myasthenia Gravis: a Pilot Study to Possible Future Implications of Treatment. CNS Neurol Disord Drug Targets. 2019;18(3):232-238 Authors: Onesti E, Frasca V, Ceccanti M, Tartaglia G, Gori MC, Cambieri C, Libonati L, Palma E, Inghilleri M Abstract BACKGROUND: The cannabinoid system may be involved in the humoral mechanisms at the neuromuscular junction. Ultramicronized-palmitoylethanolamide...
Thu Jun 18, 2020 13:41
Related ArticlesBlue Rubber Bleb Nevus Syndrome: A Possible Cause for Growth Retardation and Pubertal Delay. Med Princ Pract. 2019;28(3):294-296 Authors: Pan Y, Zhang L, Duan M, Yang H, Zhao D, Li W Abstract OBJECTIVE: The aim of this paper was to describe a rare case of blue rubber bleb nevus (BRBNS) with growth retardation and pubertal delay. CLINICAL PRESENTATION AND INTERVENTION: A 16-year-old boy with severe iron deficiency anemia was...
Thu Jun 18, 2020 13:41
Related ArticlesPathobiology and genetics of adrenocortical carcinoma. J Mol Endocrinol. 2019 02 01;62(2):R105-R119 Authors: Pittaway JFH, Guasti L Abstract Adrenocortical carcinoma (ACC) is a rare malignancy with an incidence worldwide of 0.7-2.0 cases/million/year. Initial staging is the most important factor in determining prognosis. If diagnosed early, complete surgical resection +/- adjuvant treatment can lead to 5-year survival of up to 80%. However,...
Thu Jun 18, 2020 13:41
Related ArticlesEpithelioid Hemangioma of the Thoracic Spine: A Case Report and Review of the Literature. J Spinal Cord Med. 2019 11;42(6):800-805 Authors: Okada E, Matsumoto M, Nishida M, Iga T, Morishita M, Tezuka M, Mukai K, Kobayashi E, Watanabe K Abstract Context: Osseous epithelioid hemangioma is uncommon, and reports of epithelioid hemangiomas of the spine are especially rare.Study Design: Case report.Findings: A 43-year-old male was referred...
Thu Jun 18, 2020 13:41
Related ArticlesCumulative cigarette tar exposure and lung cancer risk among Japanese smokers. Jpn J Clin Oncol. 2020 Jun 17;: Authors: Shimatani K, Ito H, Matsuo K, Tajima K, Takezaki T Abstract OBJECTIVE: Tar concentration in cigarette brands is chronologically decreasing in the USA and Japan. However, studies investigating lung cancer risk with cumulative tar exposure in Western and Asian countries are insufficient. To investigate the risk of lung...
Thu Jun 18, 2020 13:38
Related ArticlesThe first case report of polymerase proofreading-associated polyposis in POLD1 variant, c.1433G>A p.S478N, in Japan. Jpn J Clin Oncol. 2020 Jun 17;: Authors: Ito T, Nomizu T, Eguchi H, Kamae N, Dechamethakun S, Akama Y, Endo G, Sugano K, Yoshida T, Okazaki Y, Ishida H Abstract Polymerase proofreading-associated polyposis, caused by germline variants in the exonuclease domains of POLD1 and POLE, is a dominantly inherited rare condition...
Thu Jun 18, 2020 13:38
Related ArticlesSublobar resection versus lobectomy for patients with resectable stage I non-small cell lung cancer with idiopathic pulmonary fibrosis: a phase III study evaluating survival (JCOG1708, SURPRISE). Jpn J Clin Oncol. 2020 Jun 17;: Authors: Tanaka K, Tsutani Y, Wakabayashi M, Mizutani T, Aokage K, Miyata Y, Kuroda H, Saji H, Watanabe SI, Okada M, behalf of the Lung Cancer Surgical Study Group/Japan Clinical Oncology Group Abstract The standard...
Thu Jun 18, 2020 13:38
Related ArticlesReal-world use of osimertinib for epidermal growth factor receptor T790M-positive non-small cell lung cancer in Japan. Jpn J Clin Oncol. 2020 Jun 17;: Authors: Ohe Y, Kato T, Sakai F, Kusumoto M, Endo M, Saito Y, Baba T, Sata M, Yamaguchi O, Sakamoto K, Sugeno M, Tamura R, Tokimoto T, Shimizu W, Gemma A Abstract OBJECTIVE: Adverse drug reactions (ADRs) during real-world osimertinib use were investigated in Japan. METHODS: Patients...
Thu Jun 18, 2020 13:38
Many fields of modern systematic biology are adult-centred. This is unfortunately also the case for Cymothoidae, an ingroup of parasitic forms of Isopoda, with fishes as hosts. Different ingroups of Cymothoidae have specialised appendages that enable their fish associated lifestyles, attaching to different sites on the body of the host. The extent to which these structures vary among species and in relation different sites of attachment, and between different ontogenetic stages, is explored here....
Thu Jun 18, 2020 03:00
In highly biodiverse systems, such as coral reefs, prey species are faced with predatory threats from numerous species. Recognition of predators can be innate, or learned, and can help increase the chance of survival. Research suggests that parental exposure to increased predatory threats can affect the development, behaviour, and ultimately, success of their offspring. Breeding pairs of damselfish (Acanthochromis polyacanthus) were subjected to one of three olfactory and visual treatments (predator,...
Thu Jun 18, 2020 03:00
Background Echinococcosis caused by larval of Echinococcus is prevalent all over the world. Although clinical experience showed that the presence of tapeworms could not be found in liver lesions, the repeated infection and aggravation of lesions still occur in the host. Here, this study constructed a multifactor-driven disease-related dysfunction network to explore the potential molecular pathogenesis mechanism in different hosts after E.multilocularis infection. ...
Thu Jun 18, 2020 03:00
Background Melanocytes play an extremely important role in the process of skin and coat colors in mammals which is regulated by melanin-related genes. Previous studies have demonstrated that KIT is implicated in the process of determining the color of the coat in Rex rabbits. However, the effect of KIT on the proliferation and apoptosis of melanocytes and melanogenesis has not been clarified. Methods The mRNA and protein...
Thu Jun 18, 2020 03:00
Disease, pest control, and environmental factors such as water quality and carrying capacity limit growth of salmon production in existing farm areas. One way to circumvent such problems is to move production into more exposed locations with greater water exchange. Farming in exposed locations is better for the environment, but may carry unforeseen costs for the fish in those farms. Currents may be too strong, and waves may be too large with a negative impact on growth and profit for farmers and...
Thu Jun 18, 2020 03:00
The understanding of the functional properties of mitochondrial transfer RNA (mt tRNAs) depend on the knowledge of its structure. tRNA acts as an interface between polynucleotides and polypeptides thus, they are key molecules in protein biosynthesis. The tRNA molecule has a functional design and, given its importance in the translation of mitochondrial genes, it is plausible that modifications of the structure can affect the synthesis of proteins and the functional properties of the mitochondria....
Thu Jun 18, 2020 03:00
Woodpecker diversity is usually higher in natural forests rich in dead wood and old trees than in managed ones, thus this group of birds is regarded as an indicator of forest biodiversity. Woodpeckers excavate cavities which can be subsequently used by several bird species. As a consequence, their abundance indicates high avian abundance and diversity in forests. However, woodpecker-made holes may be also important for other animals, for example, mammals but it has seldom been investigated so far....
Thu Jun 18, 2020 03:00
Publication date: Available online 17 June 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): C. Qiao, D. Li, Z. Zhang, C. Shi
Thu Jun 18, 2020 13:21
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