Indian jujube (Ziziphus Mauritiana Lam) is a sweet fruit from a tree native to tropical and subtropical regions of Asia and India. A few case reports have implicated Indian jujube to cause latex-fruit syndrome. W...
Wed Jun 17, 2020 03:00
ABSTRACT Chromosome instability (CIN) generates genetic and karyotypic diversity that is common in hematological malignancies. Low to moderate levels of CIN are well tolerated and can promote cancer proliferation. However, high levels of CIN are lethal. Thus, CIN may serve both as a prognostic factor to predict clinical outcome and as a predictive biomarker. A retrospective study was performed to evaluate CIN in acute myeloid leukemia (AML). Chromosome mis‐segregation frequency was correlated with...
Wed Jun 17, 2020 21:29
Abstract Despite significant recent advances in characterizing the molecular pathogenesis of undifferentiated round cell neoplasms, rare cases remain unclassified. Herein, we report two distinctive undifferentiated round cell tumors occurring in young adults. One tumor was intrabdominal and the other arose within the abdominal wall. One patient died of disease following local and distance recurrence, despite aggressive chemotherapy and radiotherapy. Morphologically, both tumors were similarly composed...
Wed Jun 17, 2020 21:14
Related ArticlesNucleolus-Targeted Photodynamic Anticancer Therapy Using Renal-Clearable Carbon Dots. Adv Healthc Mater. 2020 Jun 16;:e2000607 Authors: Pang W, Jiang P, Ding S, Bao Z, Wang N, Wang H, Qu J, Wang D, Gu B, Wei X Abstract Photodynamic therapy (PDT), which utilizes light excited photosensitizers (PSs) to generate reactive oxygen species (ROS) and consequently ablate cancer cells or diseased tissue, has attracted a great deal of attention...
Thu Jun 18, 2020 13:11
Related ArticlesRisk stratification in oral squamous cell carcinoma using staging of the eighth American Joint Committee on Cancer: Systematic review and meta-analysis. Head Neck. 2020 Jun 17;: Authors: Almangush A, Pirinen M, Youssef O, Mäkitie AA, Leivo I Abstract The eighth edition of the American Joint Committee on Cancer (AJCC8) staging manual has major changes in oral squamous cell carcinoma (OSCC). We searched PubMed, OvidMedline, Scopus,...
Thu Jun 18, 2020 13:11
Related ArticlesHIP1R acts as a tumor suppressor in gastric cancer by promoting cancer cell apoptosis and inhibiting migration and invasion through modulating Akt. J Clin Lab Anal. 2020 Jun 16;:e23425 Authors: Zhu J, Wang X, Guan H, Xiao Q, Wu Z, Shi J, Zhang F, Gao P, Song Y, Wang Z Abstract BACKGROUND: Huntingtin-interacting protein 1-related (HIP1R) is a multi-domain gene that exerts many cellular functions including altering T cell-mediated cytotoxicity...
Thu Jun 18, 2020 13:11
Related ArticlesComputational Modeling of Interstitial Fluid Pressure and Velocity in Head and Neck Cancer Based on Dynamic Contrast-Enhanced Magnetic Resonance Imaging: Feasibility Analysis. Tomography. 2020 Jun;6(2):129-138 Authors: LoCastro E, Paudyal R, Mazaheri Y, Hatzoglou V, Oh JH, Lu Y, Konar AS, Vom Eigen K, Ho A, Ewing JR, Lee N, Deasy JO, Shukla-Dave A Abstract We developed and tested the feasibility of computational fluid modeling (CFM)...
Thu Jun 18, 2020 13:11
Related ArticlesIn silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization. Front Chem. 2020;8:443 Authors: Michel M, Homan EJ, Wiita E, Pedersen K, Almlöf I, Gustavsson AL, Lundbäck T, Helleday T, Warpman Berglund U Abstract Computational chemistry has now been widely accepted as a useful tool for shortening lead times in early drug discovery. When selecting new potential drug targets, it is important...
Thu Jun 18, 2020 13:11
Related ArticlesMesothelin expression in esophageal adenocarcinoma and squamous cell carcinoma and its possible impact on future treatment strategies. Ther Adv Med Oncol. 2020;12:1758835920917571 Authors: Moentenich V, Comut E, Gebauer F, Tuchscherer A, Bruns C, Schroeder W, Buettner R, Alakus H, Loeser H, Zander T, Quaas A Abstract Background: Mesothelin is expressed at very low levels by normal mesothelial cells but is overexpressed in several...
Thu Jun 18, 2020 13:11
Related ArticlesLooking for the Optimal PD-1/PD-L1 Inhibitor in Cancer Treatment: A Comparison in Basic Structure, Function, and Clinical Practice. Front Immunol. 2020;11:1088 Authors: Chen Y, Pei Y, Luo J, Huang Z, Yu J, Meng X Abstract Programmed cell death protein-1/ligand 1 (PD-1/L1) targeted immune checkpoint inhibitors have become the focus of tumor treatment due to their promising efficacy. Currently, several PD-1/PD-L1 inhibitors have been...
Thu Jun 18, 2020 13:11
Related ArticlesAnalysis of Virus and Host Proteomes During Productive HSV-1 and VZV Infection in Human Epithelial Cells. Front Microbiol. 2020;11:1179 Authors: Ouwendijk WJD, Dekker LJM, van den Ham HJ, Lenac Rovis T, Haefner ES, Jonjic S, Haas J, Luider TM, Verjans GMGM Abstract Herpes simplex virus 1 (HSV-1) and varicella-zoster virus (VZV) are two closely related human alphaherpesviruses that persistently infect most adults worldwide and cause...
Thu Jun 18, 2020 13:11
Skin Cancer May Delay Onset but Not Progression of Parkinson's Disease: A Nested Case-Control Study.
Related ArticlesSkin Cancer May Delay Onset but Not Progression of Parkinson's Disease: A Nested Case-Control Study. Front Neurol. 2020;11:406 Authors: Mahajan A, Chirra M, Dwivedi AK, Sturchio A, Keeling EG, Marsili L, Espay AJ Abstract Objective: To evaluate the extent to which cancer, a biological opposite to neurodegenerative disorders, may affect the onset and progression of Parkinson's disease (PD). Methods: A nested case-control design in...
Thu Jun 18, 2020 13:11
Related ArticlesProvince-specific smoking-attributable cancer mortality in China 2013. Tob Induc Dis. 2020;18:49 Authors: Yu L, Cheng J, Cui X, Wang J Abstract INTRODUCTION: Province-specific initiatives are at the forefront of tobacco control but limited studies have provided province-specific assessment of smoking-attributable cancer burden in China. METHODS: We estimated the fraction of total and site-specific cancer mortality attributable...
Thu Jun 18, 2020 13:11
Related ArticlesMini-Review: Cabozantinib in the Treatment of Advanced Renal Cell Carcinoma and Hepatocellular Carcinoma. Cancer Manag Res. 2020;12:3741-3749 Authors: Rathi N, Maughan BL, Agarwal N, Swami U Abstract Cabozantinib is an oral, tyrosine-kinase inhibitor with potent activity against VEGFR2 and MET, along with multiple other tyrosine kinases involved in cancer development and progression. Herein, we will focus on preclinical and clinical...
Thu Jun 18, 2020 13:11
Related ArticlesAdvances and Prospects of Vasculogenic Mimicry in Glioma: A Potential New Therapeutic Target? Onco Targets Ther. 2020;13:4473-4483 Authors: Cai H, Liu W, Liu X, Li Z, Feng T, Xue Y, Liu Y Abstract Vasculogenic mimicry (VM) is the formation of a "vessel-like" structure without endothelial cells. VM exists in vascular-dependent solid tumors and is a special blood supply source involved in the highly invasive tumor progression. VM is...
Thu Jun 18, 2020 13:11
Related ArticlesPatient Selection Strategies to Maximize Therapeutic Index of Antibody Drug Conjugates: Prior Approaches and Future Directions. Mol Cancer Ther. 2020 Jun 16;: Authors: Williams M, Spreafico A, Vashisht K, Hinrichs MJ Abstract Antibody drug conjugates (ADCs) are targeted agents that have shown promise in treating cancer. A central challenge in development of ADCs is the relatively narrow therapeutic index observed in clinical studies....
Thu Jun 18, 2020 13:11
Related ArticlesConcordance between predicted HLA type using next generation sequencing data generated for non-HLA purposes and clinical HLA type. Hum Immunol. 2020 Jun 13;: Authors: Moyer AM, Dukek B, Duellman P, Schneider B, Wakefield L, Skierka JM, Avula R, Bhagwate AV, Kalari KR, Kreuter JD, Goetz MP, Boughey JC, Black JL, Gandhi MJ Abstract We explored the feasibility of obtaining accurate HLA type using pre-existing NGS data not generated for...
Thu Jun 18, 2020 13:11
Related ArticlesNeoadjuvant therapy for muscle-invasive bladder cancer. Expert Rev Anticancer Ther. 2020 Jun 16;: Authors: Jain RK, Sonpavde G Abstract INTRODUCTION: Muscle-invasive bladder cancer (MIBC) is generally a highly aggressive malignancy with early and mostly distant recurrences. Cisplatin-based combinations have been established as neoadjuvant chemotherapy (NAC) prior to radical cystectomy (RC) providing overall survival as well as disease-free...
Thu Jun 18, 2020 13:11
Related ArticlesExercise before, during, and after Hospitalization for Allogeneic Hematological Stem Cell Transplant: A Feasibility Randomized Controlled Trial. J Clin Med. 2020 Jun 14;9(6): Authors: Santa Mina D, Dolan LB, Lipton JH, Au D, Camacho Pérez E, Franzese A, Alibhai SMH, Jones JM, Chang E Abstract People with cancer who undergo allogeneic hematological stem cell transplant (allo-HSCT) experience significant deconditioning that can compromise...
Thu Jun 18, 2020 13:11
Related ArticlesExisting and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors. Adv Ther. 2019 10;36(10):2638-2678 Authors: Arora S, Velichinskii R, Lesh RW, Ali U, Kubiak M, Bansal P, Borghaei H, Edelman MJ, Boumber Y Abstract In the last few years, immunotherapy has transformed the way we treat solid tumors, including melanoma, lung, head neck, breast, renal, and bladder cancers. Durable responses and long-term survival benefit...
Thu Jun 18, 2020 13:11
Related ArticlesArtificial intelligence, chatbots, and the future of medicine. Lancet Oncol. 2019 Apr;20(4):481-482 Authors: Greene A, Greene CC, Greene C PMID: 30942174 [PubMed - indexed for MEDLINE]
Thu Jun 18, 2020 13:11
Related ArticlesPrognostic factors in children with head and neck rhabdomyosarcoma: A 12-year retrospective study. Brain Behav. 2020 Jun 16;:e01697 Authors: Zhang Y, Zhang WL, Huang DS, Wang YZ, Hu HM, Mei YY, Zhi T Abstract INTRODUCTION: To identify possible prognostic factors in children with head and neck rhabdomyosarcoma (RMS). METHODS: A total of 98 patients with head and neck RMS were enrolled in this retrospective study from February...
Thu Jun 18, 2020 13:11
Related ArticlesCD8+CD73+ T cells in the tumor microenvironment of head and neck cancer patients are linked to diminished T cell infiltration and activation in tumor tissue. Eur J Immunol. 2020 Jun 16;: Authors: Panigrahi S, Bazdar DA, Albakri M, Ferrari B, Antonelli CJ, Freeman ML, Dubyak G, Zender C, Sieg SF Abstract Recent studies have implicated a role for adenosine-dependent immunosuppression in head and neck tumor microenvironments. We describe...
Thu Jun 18, 2020 13:11
Related ArticlesOssifying Lipoma in Costal Arches That Suggest Extensive Pulmonary Involvement: Case Report. Clin Pathol. 2020 Jan-Dec;13:2632010X20906166 Authors: Tobón A, Silva NM, Velásquez M, Morales E, Sangiovanni S, Fernández-Trujillo L Abstract Background: Lipomas are the most common benign soft tissue tumors in the general population. These lesions can appear on any part of the body and usually develop in the subcutaneous superficial tissue....
Thu Jun 18, 2020 13:11
Related ArticlesUsing Telemedicine and Infographics for Physician-Guided Home Drain Removal. OTO Open. 2020 Apr-Jun;4(2):2473974X20933566 Authors: Go BC, Brewster R, Patel R, Rajasekaran K Abstract Objective: Measures to decrease hospital length of stay and outpatient visits are crucial during the coronavirus disease 2019 (COVID-19) pandemic. Physician-guided home drain removal presents a potential opportunity for mitigating viral spread and transmission....
Thu Jun 18, 2020 13:11
Related ArticlesTime to Laryngoscopy for Hoarseness in Canada: Are the American Academy of Otolaryngology Guidelines Feasible? OTO Open. 2020 Apr-Jun;4(2):2473974X20932500 Authors: Howlett J, Singer J, Lee T, Hu A Abstract Objectives: To determine if a Canadian voice center is meeting the recommended time to laryngoscopy for hoarseness per the clinical practice guideline of the American Academy of Otolaryngology-Head and Neck Surgery. Study...
Thu Jun 18, 2020 13:11
Related ArticlesBrief Intervention for Tobacco when Diagnosed with Oral Cancer (BITDOC): Study protocol of a randomized clinical trial studying efficacy of brief tobacco cessation intervention, Chhattisgarh, India. Tob Prev Cessat. 2020;6:4 Authors: Singh LK, Arora RD, Tikka SK, Shukla A, Singh S, Mahant S, Verma S Abstract INTRODUCTION: Tobacco use is a major causative factor for cancer. Cessation programs along with diagnosis of cancer as a motivating...
Thu Jun 18, 2020 13:11
Related ArticlesDiffusion-Weighted Echo Planar Imaging using MUltiplexed Sensitivity Encoding and Reverse Polarity Gradient in Head and Neck Cancer: An Initial Study. Tomography. 2020 Jun;6(2):231-240 Authors: Konar AS, Fung M, Paudyal R, Oh JH, Mazaheri Y, Hatzoglou V, Shukla-Dave A Abstract We aimed to compare the geometric distortion (GD) correction performance and apparent diffusion coefficient (ADC) measurements of single-shot diffusion-weighted...
Thu Jun 18, 2020 13:11
Related ArticlesMultisite Technical and Clinical Performance Evaluation of Quantitative Imaging Biomarkers from 3D FDG PET Segmentations of Head and Neck Cancer Images. Tomography. 2020 Jun;6(2):65-76 Authors: Smith BJ, Buatti JM, Bauer C, Ulrich EJ, Ahmadvand P, Budzevich MM, Gillies RJ, Goldgof D, Grkovski M, Hamarneh G, Kinahan PE, Muzi JP, Muzi M, Laymon CM, Mountz JM, Nehmeh S, Oborski MJ, Zhao B, Sunderland JJ, Beichel RR Abstract Quantitative...
Thu Jun 18, 2020 13:11
Related ArticlesMyxofibrosarcoma of the scalp with difficult preoperative diagnosis: A case report and review of the literature. World J Clin Cases. 2020 Jun 06;8(11):2350-2358 Authors: Ke XT, Yu XF, Liu JY, Huang F, Chen MG, Lai QQ Abstract BACKGROUND: A myxofibrosarcoma (MFS) is a malignant fibroblastic tumor that tends to occur in the lower and upper extremities. The reported incidence of head and neck MFSs is extremely rare. We report a 46-year-old...
Thu Jun 18, 2020 13:11
Related ArticlesAnalysis of Genetic Alteration Signatures and Prognostic Values of m6A Regulatory Genes in Head and Neck Squamous Cell Carcinoma. Front Oncol. 2020;10:718 Authors: Zhou X, Han J, Zhen X, Liu Y, Cui Z, Yue Z, Ding L, Xu S Abstract Genetic alteration involving N6-methyladenosine (m6A) regulatory genes is a frequent characteristic of multiple tumors. Nevertheless, little is known regarding their genetic alteration signatures and prognostic...
Thu Jun 18, 2020 13:11
Related ArticlesFunctional Landscape of Dysregulated MicroRNAs in Oral Squamous Cell Carcinoma: Clinical Implications. Front Oncol. 2020;10:619 Authors: Ghosh RD, Pattatheyil A, Roychoudhury S Abstract MicroRNA (miRNA) dysregulation is associated with the pathogenesis of oral squamous cell carcinoma (OSCC), and its elucidation could potentially provide information on patient outcome. A growing body of translational research on miRNA biology is focusing...
Thu Jun 18, 2020 13:11
Related ArticlesProfiling lysophosphatidic acid levels in plasma from head and neck cancer patients. PeerJ. 2020;8:e9304 Authors: Abdul Rahman M, Mohamad Haron DE, Hollows RJ, Abdul Ghani ZDF, Ali Mohd M, Chai WL, Ng CC, Lye MS, Karsani SA, Yap LF, Paterson IC Abstract Head and neck squamous cell carcinoma (HNSCC) represents a significant world health problem, with approximately 600,000 new cases being diagnosed annually. The prognosis for patients...
Thu Jun 18, 2020 13:11
Related ArticlesBioactivity and safety of B7-H3-targeted chimeric antigen receptor T cells against anaplastic meningioma. Clin Transl Immunology. 2020;9(6):e1137 Authors: Tang X, Liu F, Liu Z, Cao Y, Zhang Z, Wang Y, Huang J, Fan S, Zhao S, Chen Y, Li G, Wang S, Zheng M, Hu Y, Li H, Jiang C, Yang M, Yang H, Xu J, Guo G, Tong A, Zhou L Abstract Objective: We conducted a first-in-human study to evaluate the bioactivity and safety of B7-H3-targeted...
Thu Jun 18, 2020 13:11
Ambient Pressure Tympanometry Wave Patterns in Patients With Superior Semicircular Canal Dehiscence.
Related ArticlesAmbient Pressure Tympanometry Wave Patterns in Patients With Superior Semicircular Canal Dehiscence. Front Neurol. 2020;11:379 Authors: Thai A, Sayyid ZN, Hosseini DK, Swanson A, Ma Y, Aaron KA, Vaisbuch Y Abstract Importance: Superior semicircular canal dehiscence (SSCD) is a treatable condition, but current diagnostic modalities have numerous limitations. Clinicians would benefit from an additional tool for diagnostic workup that...
Thu Jun 18, 2020 13:11
Related ArticlesImpact of Tussigenic Stimuli on Perceived Upper Airway Sensation and Motor Cough Response Following Total Laryngectomy. Front Physiol. 2020;11:477 Authors: Fullerton A, Mou Y, Silver N, Chheda N, Bolser DC, Wheeler-Hegland K Abstract Background: Total laryngectomy (TL) is standard intervention for carcinoma of the head and neck or, in cases of non-functional larynx, as a result of disease or radiation exposure. Laryngeal extirpation...
Thu Jun 18, 2020 13:11
Related ArticlesIL-1β Promotes Stemness of Tumor Cells by Activating Smad/ID1 Signaling Pathway. Int J Med Sci. 2020;17(9):1257-1268 Authors: Lu L, Wang P, Zou Y, Zha Z, Huang H, Guan M, Wu Y, Liu G Abstract Background: IL-1β is reported to be involved in cancer development and distant metastasis. However, the underlying mechanism of IL-1β upon malignant behaviors remains largely unknown. In this study, we aimed to study whether IL-1β could enhance...
Thu Jun 18, 2020 13:11
Related ArticlesLong Non-Coding RNA SLC25A21-AS1 Promotes Multidrug Resistance in Nasopharyngeal Carcinoma by Regulating miR-324-3p/IL-6 Axis. Cancer Manag Res. 2020;12:3949-3957 Authors: Wang X, Wang C, Xu H, Xie H Abstract Background: Nasopharyngeal carcinoma (NPC), one of the most common types of head and neck tumor, occurred in the epithelial lining of the nasopharynx and is mainly prevalent in Southeast Asia and Southern China. However, the...
Thu Jun 18, 2020 13:11
Related ArticlesmiR-381 Mediates the Development of Head and Neck Squamous Cell Carcinoma via Targeting STC2. Onco Targets Ther. 2020;13:4485-4493 Authors: Ma HF, Lv GX, Zhang DH Abstract Objective: miR-381 is implicated in the occurrence and development of various cancers, yet its role in head and neck squamous cell carcinoma (HNSCC) remains largely unknown. This study sought to research the direct target of miR-381 in HNSCC and investigate their...
Thu Jun 18, 2020 13:11
Related ArticlesPatient Satisfaction with Fentanyl Pectin Nasal Spray in Breakthrough Cancer Pain Management During Radiotherapy for Head and Neck Cancer. Patient Prefer Adherence. 2020;14:859-868 Authors: Pointreau Y, Bensadoun RJ, Bera G, Sire C, Ruffier A, Janoray G, Calais G, Bollet M, Pinel B, Braniste V, Amores X Abstract Objective: The severity of breakthrough cancer pain (BTcP) impacts patients' quality of life, increases the risk of anxiety...
Thu Jun 18, 2020 13:11
Related ArticlesRelations between body mass index, laryngeal fat pads, and laryngeal airway configuration in adult men population. Int J Obes (Lond). 2020 Jun 16;: Authors: Lahav Y, Adi M, Arberboy E, Halperin D, Shoffel-Havakuk H, Cohen O Abstract BACKGROUND: The impact of body mass index (BMI) on pharyngeal fat pads has been well studied, yet no study has assessed its associations on laryngeal morphology. OBJECTIVES: To study the associations...
Thu Jun 18, 2020 13:11
Related ArticlesDifferential therapeutic effects of PARP and ATR inhibition combined with radiotherapy in the treatment of subcutaneous versus orthotopic lung tumour models. Br J Cancer. 2020 Jun 17;: Authors: Tran Chau V, Liu W, Gerbé de Thoré M, Meziani L, Mondini M, O'Connor MJ, Deutsch E, Clémenson C Abstract BACKGROUND: Subcutaneous mouse tumour models are widely used for the screening of novel antitumour treatments, although these models are...
Thu Jun 18, 2020 13:11
Related ArticlesERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy. Pharmacogenomics J. 2020 Jun 16;: Authors: Guberina M, Sak A, Pöttgen C, Tinhofer-Keilholz I, Budach V, Balermpas P, Von der Grün J, Rödel CM, Gikka E, Grosu AL, Abdollahi A, Debus J, Belka C, Pigorsch S, Combs S, Mönnich D, Zips D, De-Colle C, Welz S, Linge A, Lohaus F, Baretton G, Gauler...
Thu Jun 18, 2020 13:11
Related ArticlesIdentification of candidate aberrantly methylated and differentially expressed genes in Esophageal squamous cell carcinoma. Sci Rep. 2020 Jun 16;10(1):9735 Authors: Han BA, Yang XP, Hosseini DK, Zhang P, Zhang Y, Yu JT, Chen S, Zhang F, Zhou T, Sun HY Abstract Aberrant methylated genes (DMGs) play an important role in the etiology and pathogenesis of esophageal squamous cell carcinoma (ESCC). In this study, we aimed to integrate three...
Thu Jun 18, 2020 13:11
Related ArticlesA common rule governing differentiation kinetics of mouse cortical progenitors. Proc Natl Acad Sci U S A. 2020 Jun 16;: Authors: Sahara S, Kodama T, Stevens CF Abstract The balance between proliferation and differentiation of stem cells and progenitors determines the size of an adult brain region. While the molecular mechanisms regulating proliferation and differentiation of cortical progenitors have been intensively studied, an analysis...
Thu Jun 18, 2020 13:11
Related ArticlesAdvances in the diagnosis and management of IgG4 related disease. BMJ. 2020 Jun 16;369:m1067 Authors: Lanzillotta M, Mancuso G, Della-Torre E Abstract IgG4 related disease was recognized as a unified disease entity only 15 years ago. Awareness of IgG4 related disease has increased worldwide since then, and specialists are now familiar with most of its clinical manifestations. Involvement of the pancreato-biliary tract, retroperitoneum/aorta,...
Thu Jun 18, 2020 13:11
Related ArticlesLoss of PTEN sensitizes head and neck squamous cell carcinoma to 5-AZA-2'-deoxycytidine. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 16;: Authors: Borgato GB, Borges GA, Souza AP, Squarize CH, Castilho RM Abstract OBJECTIVE: Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer associated with poor survival. Phosphatase and tensin homolog (PTEN) is a tumor suppressor gene involved in the maintenance of stem...
Thu Jun 18, 2020 13:11
Related ArticlesA Systematic Review on Outcomes of Anterior Skull Base Reconstruction. J Plast Reconstr Aesthet Surg. 2020 May 25;: Authors: Lim X, Rajagopal R, Silva P, Jeyaretna DS, Mykula R, Potter M Abstract INTRODUCTION: Anterior skull base resection often results in large defects that need to be reconstructed. This can be done using loco-regional, free flaps or both. OBJECTIVE: The aim of this systematic review is to evaluate the...
Thu Jun 18, 2020 13:11
Related ArticlesContrast-enhanced ultrasound sonography combined with strain elastography to evaluate mandibular lymph nodes in clinically healthy dogs and those with head and neck tumors. Vet J. 2020 Mar;257:105447 Authors: Choi M, Yoon J, Choi M Abstract Determining lymph node metastases in dogs with neoplasia is important in staging and developing a therapeutic plan. In this study, the clinical efficacy of combined lymphosonography and strain...
Thu Jun 18, 2020 13:11
Related ArticlesIn reference to 'Magnetic resonance imaging of Ménière's disease: early clinical experience in a UK centre'. J Laryngol Otol. 2020 Jun 17;:1 Authors: Karthikeyan P, Rasmika K PMID: 32546283 [PubMed - as supplied by publisher]
Thu Jun 18, 2020 13:11
Related ArticlesIncreased risk of tinnitus in patients with early-onset cataracts: a nationwide population-based case-control study. BMC Ophthalmol. 2020 Jun 16;20(1):230 Authors: Hsieh YC, Chang CH, Tsai YY, Lin CL, Ng TY, Chiang CC Abstract BACKGROUND: This study aimed to investigate the association between early-onset cataract and tinnitus using a population-based database. METHODS: Retrospective claims data from the Taiwan National...
Thu Jun 18, 2020 13:11
Related ArticlesInteraction between obstructive sleep apnea and short sleep duration on insulin resistance: a large-scale study : OSA, short sleep duration and insulin resistance. Respir Res. 2020 Jun 16;21(1):151 Authors: Xu H, Liang C, Zou J, Yi H, Guan J, Gu M, Feng Y, Yin S Abstract OBJECTIVES: Both short sleep duration and obstructive sleep apnea (OSA) seem to be associated with insulin resistance. We aimed to explore whether short sleep duration...
Thu Jun 18, 2020 13:11
Related ArticlesOral Cavity Cancer Outcomes in Remote, Betel Nut-Endemic Pacific Islands. Ann Otol Rhinol Laryngol. 2020 Jun 16;:3489420934846 Authors: Narayanan AM, Finegersh AF, Chang MP, Orosco RK, Moss WJ Abstract BACKGROUND: Oral cavity carcinomas individually are the fifth-leading cause of overall cancer mortality in the Northern Mariana Islands, which is likely a representative statistic for many other betel-nut-endemic Pacific islands. Factors...
Thu Jun 18, 2020 13:11
Related ArticlesVariation in Chin and Mandibular Symphysis Size and Shape in Males and Females: A CT-Based Study. Int J Environ Res Public Health. 2020 Jun 14;17(12): Authors: Sella Tunis T, Hershkovitz I, May H, Vardimon AD, Sarig R, Shpack N Abstract The chin is a unique anatomical landmark of modern humans. Its size and shape play an important role from the esthetic perspective. However, disagreement exists in the dental and anthropological literature...
Thu Jun 18, 2020 13:11
Related ArticlesExtract of Juniperus indica Bertol Synergizes with Cisplatin to Inhibit Oral Cancer Cell Growth via Repression of Cell Cycle Progression and Activation of the Caspase Cascade. Molecules. 2020 Jun 13;25(12): Authors: Huang XF, Chang KF, Lee SC, Li CY, Liao HH, Hsieh MC, Tsai NM Abstract Oral cancer-a type of head and neck cancer-is estimated to be the fifth most common cancer in Taiwan. However, efficacious therapies for oral cancer...
Thu Jun 18, 2020 13:11
Related ArticlesCirculating Plasma Gelsolin: A Predictor of Favorable Clinical Outcomes in Head and Neck Cancer and Sensitive Biomarker for Early Disease Diagnosis Combined with Soluble Fas Ligand. Cancers (Basel). 2020 Jun 13;12(6): Authors: Chiu CT, Wang PW, Asare-Werehene M, Tsang BK, Shieh DB Abstract Head and neck cancer (HNC) accounts for more than 330,000 cancer deaths annually worldwide. Despite late diagnosis being a major factor contributing...
Thu Jun 18, 2020 13:11
Related ArticlesActivating the DNA Damage Response and Suppressing Innate Immunity: Human Papillomaviruses Walk the Line. Pathogens. 2020 Jun 13;9(6): Authors: James CD, Das D, Bristol ML, Morgan IM Abstract Activation of the DNA damage response (DDR) by external agents can result in DNA fragments entering the cytoplasm and activating innate immune signaling pathways, including the stimulator of interferon genes (STING) pathway. The consequences...
Thu Jun 18, 2020 13:11
NO Candida auris: Nitric Oxide in Nanotherapeutics to Combat Emerging Fungal Pathogen Candida auris.
Related ArticlesNO Candida auris: Nitric Oxide in Nanotherapeutics to Combat Emerging Fungal Pathogen Candida auris. J Fungi (Basel). 2020 Jun 12;6(2): Authors: Cleare LG, Li KL, Abuzeid WM, Nacharaju P, Friedman JM, Nosanchuk JD Abstract Candida auris (C. auris) is an emerging pathogenic fungal species that is especially worrisome due to its high mortality rates and widespread antifungal resistance. Previous studies have demonstrated the efficacy...
Thu Jun 18, 2020 13:11
Related ArticlesThe Evolution of Care of Cancers of the Head and Neck Region: State of the Science in 2020. Cancers (Basel). 2020 Jun 11;12(6): Authors: Yan F, Knochelmann HM, Morgan PF, Kaczmar JM, Neskey DM, Graboyes EM, Nguyen SA, Ogretmen B, Sharma AK, Day TA Abstract Cancers that arise in the head and neck region are comprised of a heterogeneous group of malignancies that include carcinogen- and human papillomavirus (HPV)-driven mucosal squamous...
Thu Jun 18, 2020 13:11
Related ArticlesPhase I Study of Ficlatuzumab and Cetuximab in Cetuximab-Resistant, Recurrent/Metastatic Head and Neck Cancer. Cancers (Basel). 2020 Jun 11;12(6): Authors: Bauman JE, Ohr J, Gooding WE, Ferris RL, Duvvuri U, Kim S, Johnson JT, Soloff AC, Wallweber G, Winslow J, Gaither-Davis A, Grandis JR, Stabile LP Abstract Cetuximab, an anti-EGFR monoclonal antibody (mAb), is approved for advanced head and neck squamous cell carcinoma (HNSCC) but...
Thu Jun 18, 2020 13:11
Related ArticlesMass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer. Cancers (Basel). 2020 Jun 11;12(6): Authors: Wurlitzer M, Möckelmann N, Kriegs M, Vens M, Omidi M, Hoffer K, Bargen CV, Möller-Koop C, Witt M, Droste C, Oetting A, Petersen H, Busch CJ, Münscher A, Schlüter H, Clauditz TS, Rieckmann T Abstract Squamous cell carcinoma of the head and neck (HNSCC) consist of two distinct biological entities. While the...
Thu Jun 18, 2020 13:11
Related ArticlesLetter to the Editor Regarding "Investigating the Gender Pay Gap in Industry Contributions to Academic Neurosurgeons". World Neurosurg. 2020 Jun;138:574-575 Authors: Silva NA, Cerasiello SY, Behmer Hansen RT, Liu JK, Eloy JA PMID: 32545001 [PubMed - in process]
Thu Jun 18, 2020 13:11
Related ArticlesReply. AJNR Am J Neuroradiol. 2020 03;41(3):E16 Authors: Roberts DR, Asemani D, Nietert PJ, Eckert MA, Inglesby DC, Bloomberg JJ, George MS, Brown TR PMID: 32079596 [PubMed - indexed for MEDLINE]
Thu Jun 18, 2020 13:11
Related ArticlesTraction force microscopy for understanding cellular mechanotransduction. BMB Rep. 2020 Feb;53(2):74-81 Authors: Hur SS, Jeong JH, Ban MJ, Park JH, Yoon JK, Hwang Y Abstract Under physiological and pathological conditions, mechanical forces generated from cells themselves or transmitted from extracellular matrix (ECM) through focal adhesions (FAs) and adherens junctions (AJs) are known to play a significant role in regulating various...
Thu Jun 18, 2020 13:11
Related ArticlesPhase II Trial of De-Intensified Chemoradiotherapy for Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma. J Clin Oncol. 2019 10 10;37(29):2661-2669 Authors: Chera BS, Amdur RJ, Green R, Shen C, Gupta G, Tan X, Knowles M, Fried D, Hayes N, Weiss J, Grilley-Olson J, Patel S, Zanation A, Hackman T, Zevallos J, Blumberg J, Patel S, Kasibhatla M, Sheets N, Weissler M, Yarbrough W, Mendenhall W Abstract PURPOSE: To report...
Thu Jun 18, 2020 13:11
Related ArticlesSustained envelope periodicity representations are associated with speech-in-noise performance in difficult listening conditions for younger and older adults. J Neurophysiol. 2019 10 01;122(4):1685-1696 Authors: McClaskey CM, Dias JW, Harris KC Abstract Temporal modulations are an important part of speech signals. An accurate perception of these time-varying qualities of sound is necessary for successful communication. The current study...
Thu Jun 18, 2020 13:11
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