Antibiotics, Vol. 9, Pages 339: The Basis for Natural Multiresistance to Phage in Pseudomonas aeruginosa Antibiotics doi: 10.3390/antibiotics9060339 Authors: Pourcel Midoux Vergnaud Latino Pseudomonas aeruginosa is responsible for long-term infections and is particularly resistant to treatments when hiding inside the extracellular matrix or biofilms. Phage therapy might represent an alternative to antibiotic treatment, but up to 10% of clinical strains appear to resist multiple...
Antibiotics, Vol. 9, Pages 340: Alkaloids from Marine Fungi: Promising Antimicrobials Antibiotics doi: 10.3390/antibiotics9060340 Authors: Willems De Mol De Bruycker De Maeseneire Soetaert Resistance of pathogenic microorganisms against antimicrobials is a major threat to contemporary human society. It necessitates a perpetual influx of novel antimicrobial compounds. More specifically, Gram− pathogens emerged as the most exigent danger. In our continuing quest...
Antibiotics, Vol. 9, Pages 338: Antibiotic Stewardship in Staphylococcus aureus Bloodstream Infection Treatment—Analysis Based on 29,747 Patients from One Hospital Antibiotics doi: 10.3390/antibiotics9060338 Authors: Ziółkowski Pawłowska Jachowicz Stasiowski Some of the most serious healthcare-associated infections (HAI) are highly deadly bloodstream infections (BSIs) caused by Staphylococcus aureus. The aim of the study was to analyse compliance of treatment practice with...
Antibiotics, Vol. 9, Pages 342: Antibiotic Resistance in Nosocomial Bacteria Isolated from Infected Wounds of Hospitalized Patients in Czech Republic Antibiotics doi: 10.3390/antibiotics9060342 Authors: Milan Kolar Pavel Cermak Lenka Hobzova Katerina Bogdanova Katerina Neradova Patrik Mlynarcik Pavel Bostik Hospitalized patients with wounds face an increased risk of infection with multi-drug-resistant nosocomial bacteria. In this study, samples from almost 10,000 patients...
Antibiotics, Vol. 9, Pages 335: Using GFP-Tagged Escherichia coli to Investigate the Persistence of Fecal Bacteria in Vegetated Wetlands: An Experimental Approach Antibiotics doi: 10.3390/antibiotics9060335 Authors: Emilia Chiapponi Charles Henriot Xavier Bertrand Didier Hocquet Gudrun Bornette The contamination of surface water by pathogenic bacteria of human origin is an important public health issue. Wetlands can be contaminated with fecal bacteria by water originating...
Antibiotics, Vol. 9, Pages 336: Stilbenoids: A Natural Arsenal against Bacterial Pathogens Antibiotics doi: 10.3390/antibiotics9060336 Authors: Luce Micaela Mattio Giorgia Catinella Sabrina Dallavalle Andrea Pinto The escalating emergence of resistant bacterial strains is one of the most important threats to human health. With the increasing incidence of multi-drugs infections, there is an urgent need to restock our antibiotic arsenal. Natural products are an invaluable source...
Antibiotics, Vol. 9, Pages 337: Metal–Peptide Complexes as Promising Antibiotics to Fight Emerging Drug Resistance: New Perspectives in Tuberculosis Antibiotics doi: 10.3390/antibiotics9060337 Authors: Concetta Di Natale Ilaria De Benedictis Arianna De Benedictis Daniela Marasco In metal-peptide interactions, cations form stable complexes through bonds with coordinating groups as side chains of amino acids. These compounds, among other things, exert a wide variety of antimicrobial...
Antibiotics, Vol. 9, Pages 334: Phytochemical Compositions and Biological Activities of Essential Oils from the Leaves, Rhizomes and Whole Plant of Hornstedtia bella Škorničk Antibiotics doi: 10.3390/antibiotics9060334 Authors: Matthew Gavino Donadu Nhan Trong Le Duc Viet Ho Tuan Quoc Doan Anh Tuan Le Ain Raal Marianna Usai Mauro Marchetti Giuseppina Sanna Silvia Madeddu Paola Rappelli Nicia Diaz Paola Molicotti Antonio Carta Sandra Piras Donatella...
Antibiotics, Vol. 9, Pages 341: Breast Abscesses Caused by Anaerobic Microorganisms: Clinical and Microbiological Characteristics Antibiotics doi: 10.3390/antibiotics9060341 Authors: Fernando Cobo Vicente Guillot José María Navarro-Marí The objectives of this study were to report the antimicrobial susceptibility of 35 clinically significant anaerobic bacteria isolated from breast abscesses between March 2017 and February 2020 in a tertiary hospital in Granada (Spain) and to describe...
Antibiotics, Vol. 9, Pages 333: In Vitro Toxicity, Antioxidant, Anti-Inflammatory, and Antidiabetic Potential of Sphaerostephanos unitus (L.) Holttum Antibiotics doi: 10.3390/antibiotics9060333 Authors: Marimuthu Alias Antonisamy Johnson C. Xavier Madona Ray S. Almeida Natália Martins Henrique D. M. Coutinho Pteridophytes have been widely used in several systems of medicine. Several reports have increasingly assessed their bioactive effects, but for Sphaerostephanos unitus...
Antibiotics, Vol. 9, Pages 332: Methicillin-Resistant Staphylococcus aureus: Risk for General Infection and Endocarditis Among Athletes Antibiotics doi: 10.3390/antibiotics9060332 Authors: Mariarita Brancaccio Cristina Mennitti Sonia Laneri Adelaide Franco Margherita G. De Biasi Arturo Cesaro Fabio Fimiani Elisabetta Moscarella Felice Gragnano Cristina Mazzaccara Giuseppe Limongelli Giulia Frisso Barbara Lombardo Chiara Pagliuca Roberta Colicchio Paola...
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Antioxidants, Vol. 9, Pages 534: Impact of Different Pasteurization Techniques and Subsequent Ultrasonication on the In Vitro Bioaccessibility of Carotenoids in Valencia Orange (Citrus sinensis (L.) Osbeck) Juice Antioxidants doi: 10.3390/antiox9060534 Authors: Etzbach Stolle Anheuser Herdegen Schieber Weber The effects of traditional pasteurization (low pasteurization, conventional pasteurization, hot filling) and alternative pasteurization (pulsed electric fields,...
Antioxidants, Vol. 9, Pages 533: Identification of Chemical Profiles and Biological Properties of Rhizophora racemosa G. Mey. Extracts Obtained by Different Methods and Solvents Antioxidants doi: 10.3390/antiox9060533 Authors: Chiavaroli Sinan Zengin Mahomoodally Sadeer Etienne Cziáky Jekő Glamocilja Sokovic Recinella Brunetti Leone Abdullah Angelini Flores Venanzoni Menghini Orlando Ferrante Mangrove forests...
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Atmosphere, Vol. 11, Pages 651: Investigation of Non-Methane Hydrocarbons at a Central Adriatic Marine Site Mali Lošinj, Croatia Atmosphere doi: 10.3390/atmos11060651 Authors: Glenda Herjavić Brunislav Matasović Gregor Arh Elvira Kovač-Andrić For the first time, volatile hydrocarbons were measured in Croatia, at Mali Lošinj in the period from autumn 2004 to autumn 2005. Mali Lošinj site is conveniently located as a gateway to Croatia for any potential pollution...
Atmosphere, Vol. 11, Pages 650: The Problems of Passive Remote Sensing of the Earth’s Surface in the Range of 1.2–1.6 GHz Atmosphere doi: 10.3390/atmos11060650 Authors: Golubkov Manzhelii Berlin Eppelbaum Lushnikov Morozov Dmitriev Adamson Dyakov Morozov Golubkov The main problems of remote sensing of the Earth’s surface within the frequency range 1.2–1.6 GHz are discussed. They are related to the resonant quantum properties...
Atmosphere, Vol. 11, Pages 648: Agricultural Water Vulnerability under Climate Change in Cyprus Atmosphere doi: 10.3390/atmos11060648 Authors: Papadopoulou Charchousi Spanoudaki Karali Varotsos Giannakopoulos Markou Loizidou This study focuses on the quantification of climate change (CC) effects on agricultural water availability in Cyprus. Projections of climatic variables, based on Regional Climate Models (RCMs) forced by the Representative Concentration...
Atmosphere, Vol. 11, Pages 649: Tropical Atlantic Mixed Layer Buoyancy Seasonality: Atmospheric and Oceanic Physical Processes Contributions Atmosphere doi: 10.3390/atmos11060649 Authors: Camara Mignot Kolodziejczyk Losada Lazar This study investigates the physical processes controlling the mixed layer buoyancy using a regional configuration of an ocean general circulation model. Processes are quantified by using a linearized equation of state, a mixed-layer heat, and...
Atmosphere, Vol. 11, Pages 647: Simulation of Wind Speed Based on Different Driving Datasets and Parameterization Schemes Near Dunhuang Wind Farms in Northwest of China Atmosphere doi: 10.3390/atmos11060647 Authors: Tiejun Zhang Cailing Zhao Chongshui Gong ZhaoXia Pu In this study, we evaluate the impacts of different datasets (e.g., NCEP global forecast system (GFS) and ERA5) that are used to derive the initial and boundary conditions, various planetary parameterization boundary...
Atmosphere, Vol. 11, Pages 646: Atmospheric Pollutant Dispersion over Complex Terrain: Challenges and Needs for Improving Air Quality Measurements and Modeling Atmosphere doi: 10.3390/atmos11060646 Authors: Lorenzo Giovannini Enrico Ferrero Thomas Karl Mathias W. Rotach Chantal Staquet Silvia Trini Castelli Dino Zardi Pollutant dispersion processes over complex terrain are much more complicated than over flat areas, as they are affected by atmospheric interactions with...
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Behavioral Sciences, Vol. 10, Pages 102: Child Wantedness and Low Weight at Birth: Differential Parental Investment among Roma Behavioral Sciences doi: 10.3390/bs10060102 Authors: Jelena Čvorović Studies investigating child wantedness, birthweight and parental care are limited. This study assessed relationships of child wantedness, low birthweight and differential parental investment in a poor population of Serbian Roma. Data from the Multiple Indicator Cluster Survey round 5 for Roma...
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Bioengineering, Vol. 7, Pages 60: A Pilot Study on Linking Tissue Mechanics with Load-Dependent Collagen Microstructures in Porcine Tricuspid Valve Leaflets Bioengineering doi: 10.3390/bioengineering7020060 Authors: Luke T. Hudson Samuel V. Jett Katherine E. Kramer Devin W. Laurence Colton J. Ross Rheal A. Towner Ryan Baumwart Ki Moo Lim Arshid Mir Harold M. Burkhart Yi Wu Chung-Hao Lee The tricuspid valve (TV) is composed of three leaflets that coapt...
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Biomedicines, Vol. 8, Pages 166: Mitochondrial Dysfunction and DNA Damage in the Context of Pathogenesis of Atherosclerosis Biomedicines doi: 10.3390/biomedicines8060166 Authors: Taisiia Shemiakova Ekaterina Ivanova Andrey V. Grechko Elena V. Gerasimova Igor A. Sobenin Alexander N. Orekhov Atherosclerosis is a multifactorial disease of the cardiovascular system associated with aging, inflammation, and oxidative stress. An important role in the development of atherosclerosis...
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Biomolecules, Vol. 10, Pages 928: ORP5 and ORP8: Sterol Sensors and Phospholipid Transfer Proteins at Membrane Contact Sites? Biomolecules doi: 10.3390/biom10060928 Authors: Nina Criado Santos Vladimir Girik Paula Nunes-Hasler Oxysterol binding related proteins 5 and 8 (ORP5 and ORP8) are two close homologs of the larger oxysterol binding protein (OSBP) family of sterol sensors and lipid transfer proteins (LTP). Early studies indicated these transmembrane proteins, anchored to...
Biomolecules, Vol. 10, Pages 927: Circulating miRNAs: A New Opportunity in Bone Fragility Biomolecules doi: 10.3390/biom10060927 Authors: Simone Donati Simone Ciuffi Gaia Palmini Maria Luisa Brandi Osteoporosis, one of the leading causes of bone fractures, is characterized by low bone mass and structural deterioration of bone tissue, which are associated with a consequent increase in bone fragility and predisposition to fracture. Current screening tools are limited in estimating...
Biomolecules, Vol. 10, Pages 930: 8-Hydroxyquinoline-2-Carboxylic Acid as Possible Molybdophore: A Multi-Technique Approach to Define Its Chemical Speciation, Coordination and Sequestering Ability in Aqueous Solution Biomolecules doi: 10.3390/biom10060930 Authors: Arena Brancato Cacciola Crea Cataldo De Stefano Gama Lando Milea Mondello Pettignano Plass Sammartano 8-hydroxyquinoline-2-carboxylic acid (8-HQA) has been found in high concentrations...
Biomolecules, Vol. 10, Pages 929: Genome-Wide Identification of RNA Silencing-Related Genes and Their Expressional Analysis in Response to Heat Stress in Barley (Hordeum vulgare L.) Biomolecules doi: 10.3390/biom10060929 Authors: Éva Hamar Henrik Mihály Szaker András Kis Ágnes Dalmadi Fabio Miloro György Szittya János Taller Péter Gyula Tibor Csorba Zoltán Havelda Barley (Hordeum vulgare L.) is an economically important crop cultivated in temperate climates...
Biomolecules, Vol. 10, Pages 925: Caudatin Isolated from Cynanchum auriculatum Inhibits Breast Cancer Stem Cell Formation via a GR/YAP Signaling Biomolecules doi: 10.3390/biom10060925 Authors: Xing Zhen Hack Sun Choi Ji-Hyang Kim Su-Lim Kim Ren Liu Yu-Chan Ko Bong-Sik Yun Dong-Sun Lee In the complex tumor microenvironment, cancer stem cells (CSCs), a rare population of cells, are responsible for malignant tumor initiation, metastasis, drug resistance and recurrence....
Biomolecules, Vol. 10, Pages 924: Redox-Dependent Copper Ion Modulation of Amyloid-β (1-42) Aggregation In Vitro Biomolecules doi: 10.3390/biom10060924 Authors: Nima Sasanian David Bernson Istvan Horvath Pernilla Wittung-Stafshede Elin K. Esbjörner Plaque deposits composed of amyloid-β (Aβ) fibrils are pathological hallmarks of Alzheimer’s disease (AD). Although copper ion dyshomeostasis is apparent in AD brains and copper ions are found co-deposited...
Biomolecules, Vol. 10, Pages 926: Implications of the Adiponectin System in Non-Small Cell Lung Cancer Patients: A Case-Control Study Biomolecules doi: 10.3390/biom10060926 Authors: Ersilia Nigro Fabio Perrotta Maria Ludovica Monaco Rita Polito Pia Clara Pafundi Maria Gabriella Matera Aurora Daniele Andrea Bianco Alterations of adipose tissue occurring in obesity have been recognized as a major risk factor for several cancers. The relationship between adipose tissue...
Biomolecules, Vol. 10, Pages 923: Antioxidant-Based Medicinal Properties of Stingless Bee Products: Recent Progress and Future Directions Biomolecules doi: 10.3390/biom10060923 Authors: Mohammad A. I. Al-Hatamleh Jennifer C. Boer Kirsty L. Wilson Magdalena Plebanski Rohimah Mohamud Mohd Zulkifli Mustafa Stingless bees are a type of honey producers that commonly live in tropical countries. Their use for honey is being abandoned due to its limited production. However, the...
Biomolecules, Vol. 10, Pages 922: Role of Lipopolysaccharide in Protecting OmpT from Autoproteolysis during In Vitro Refolding Biomolecules doi: 10.3390/biom10060922 Authors: Gaurav Sinsinbar Sushanth Gudlur Kevin J Metcalf Milan Mrksich Madhavan Nallani Bo Liedberg Outer membrane protease (OmpT) is a 33.5 kDa aspartyl protease that cleaves at dibasic sites and is thought to function as a defense mechanism for E. coli against cationic antimicrobial peptides secreted by...
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Brain Sciences, Vol. 10, Pages 385: Microstructural Changes in Motor Functional Conversion Disorder: Multimodal Imaging Approach on a Case Brain Sciences doi: 10.3390/brainsci10060385 Authors: Mariachiara Longarzo Carlo Cavaliere Giulia Mele Stefano Tozza Liberatore Tramontano Vincenzo Alfano Marco Aiello Marco Salvatore Dario Grossi Background: Functional motor conversion disorders are characterized by neurological symptoms unrelated to brain structural lesions....
Brain Sciences, Vol. 10, Pages 386: Cholesterol and Alzheimer’s Disease Risk: A Meta-Meta-Analysis Brain Sciences doi: 10.3390/brainsci10060386 Authors: Olalla Sáiz-Vazquez Alicia Puente-Martínez Silvia Ubillos-Landa Joaquín Pacheco-Bonrostro Javier Santabárbara Background: Alzheimer’s disease (AD) is the most common subtype of dementia. In the last ten years, the relationship between cholesterol and AD has been investigated. Evidence suggests that cholesterol is...
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Cancers, Vol. 12, Pages 1622: Cellular Plasticity and Tumor Microenvironment in Gliomas: The Struggle to Hit a Moving Target Cancers doi: 10.3390/cancers12061622 Authors: Gargini Segura-Collar Sánchez-Gómez Brain tumors encompass a diverse group of neoplasias arising from different cell lineages. Tumors of glial origin have been the subject of intense research because of their rapid and fatal progression. From a clinical point of view, complete surgical resection of gliomas...
Cancers, Vol. 12, Pages 1623: HLA Class I Allele Expression and Clinical Outcome in De Novo Metastatic Prostate Cancer Cancers doi: 10.3390/cancers12061623 Authors: Stokidis Fortis Kogionou Anagnostou Perez Baxevanis The prognostic value of human leukocyte antigen (HLA) class I molecules in prostate cancer (PCa) remains unclear. Herein, we investigated the prognostic relevance of the most frequently expressed HLA-A alleles in Greece (A*02:01 and HLA-A*24:02) in de...
Cancers, Vol. 12, Pages 1620: Comparison of Hodgkin’s Lymphoma in Children and Adolescents. A Twenty Year Experience with MH’96 and LH2004 AIEOP (Italian Association of Pediatric Hematology and Oncology) Protocols Cancers doi: 10.3390/cancers12061620 Authors: Roberta Burnelli Giulia Fiumana Roberto Rondelli Marta Pillon Alessandra Sala Alberto Garaventa Emanuele S.G. DAmore Elena Sabattini Salvatore Buffardi Maurizio Bianchi Luciana Vinti Marco Zecca Paola...
Cancers, Vol. 12, Pages 1619: Systemic Inflammation and Activation of Haemostasis Predict Poor Prognosis and Response to Chemotherapy in Patients with Advanced Lung Cancer Cancers doi: 10.3390/cancers12061619 Authors: Florian Moik Sabine Zöchbauer-Müller Florian Posch Ingrid Pabinger Cihan Ay Systemic inflammation and activation of haemostasis are common in patients with lung cancer. Both conditions support tumour growth and metastasis. Therefore, inflammatory and haemostatic...
Cancers, Vol. 12, Pages 1621: Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells Cancers doi: 10.3390/cancers12061621 Authors: Jennifer Beauvarlet Rabindra Nath Das Karla Alvarez-Valadez Isabelle Martins Alexandra Muller Elodie Darbo Elodie Richard Pierre Soubeyran Guido Kroemer Jean Guillon Jean-Louis Mergny Mojgan Djavaheri-Mergny Lysosomes play a key role in regulating...
Cancers, Vol. 12, Pages 1618: Rare Tumor-Normal Matched Whole Exome Sequencing Identifies Novel Genomic Pathogenic Germline and Somatic Aberrations Cancers doi: 10.3390/cancers12061618 Authors: Ryan Sprissler Bryce Perkins Laurel Johnstone Hani M Babiker Pavani Chalasani Branden Lau Michael Hammer Daruka Mahadevan Whole exome sequencing (WES) of matched tumor-normal pairs in rare tumors has the potential to identify genome-wide mutations and copy number alterations...
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