Poorva Vias, Shabnum Thakur, Rajeev K Seam, Vikas Fotedar, Ashish SaklaniClinical Cancer Investigation Journal 2019 8(2):73-75 Ewing's sarcoma is the 2nd most common paediatric bone tumour but can also be seen in extraskeletal sites. Superficial extraskeletal ES is a rare entity and is rarely seen in foot. Majority of these patients are females in second decade of life, presenting with small, single mass, mobile, sometimes painful. They usually have a favourable outcome due to infrequent metastasis.
Babak Izadi, Somayeh Jalilian, Mazaher Ramezani, Masoud Sadeghi, Sedigheh KhazaeiClinical Cancer Investigation Journal 2019 8(2):64-69 Introduction: Thyroid cancer is reported as the most rapidly increasing and third-most common cancer among females. This study aimed to evaluate the data related to thyroid cancer in Kermanshah, Iran, for the first time. Materials and Methods: The data of thyroid cancers were obtained between March 2008 and March 2017. Tumors were classified into four groups: papillary,...
Mohammad Akheel, Rinku K George, Amit Jain, Qutubuddin Chahwala, Ashmi WadhwaniaClinical Cancer Investigation Journal 2019 8(2):47-51 Background: To find out whether surgical margins and nodal metastasis are prognostic factors in oral squamous cell carcinoma (OSCC). Materials and Methods: PubMed search was done to look for studies done on surgical margins and nodal metastasis of OSCC from 2008 to 2018. Results: Fixed effects meta-analysis showed a pooled estimate absolute risk reduction of −3%...
Anubhuti Singh, Anand Srivastava, Abhishek Verma, Rajiv GargClinical Cancer Investigation Journal 2019 8(2):41-46 Context: Oral tyrosine kinase inhibitors (TKIs) have been proven to improve response rates (RRs) and progression-free survival in a chemo-naïve setting in the epidermal growth factor receptor (EGFR)-mutant advanced lung adenocarcinoma patients in studies conducted in Western countries. Similar data from India are currently sparse. Aims: The aim is to study the epidemiological, clinical,...
Hamid Ahmadi, Bita Eslami, Sadaf Alipour, Adel Yazdankhahkenary, Ramesh OmranipourClinical Cancer Investigation Journal 2019 8(2):52-56 Background: The incidence of obesity as one of the risk factors of breast cancer (BC) is increasing dramatically. Our objective was to evaluate the association between body mass index (BMI) and three subtypes of BC in Iranian women. Materials and Methods: In this retrospective study, BC patients' information was recorded by referring to their medical records in...
Milind Anil BhatkuleClinical Cancer Investigation Journal 2019 8(2):70-72 Metaplastic carcinoma of the breast is a rare entity. Extensive chondroid differentiation is even rarer in metaplastic breast carcinoma (MBC). Here, we report a case of metaplastic chondroid carcinoma of the breast with very few areas showing usual ductal carcinoma and pseudosarcomatous areas. The tumor was characterized by an abundant chondromyxoid matrix. The definitive areas of classic invasive ductal carcinoma were very...
Esra Oz, Zehra Bozdag, Neslihan Bayramoglu Tepe, Zeynep Bayramoglu, Omer Faruk Dizibuyuk, Metin KarakokClinical Cancer Investigation Journal 2019 8(2):57-63 Background: Ovarian cancer is the second most common gynecologic cancer in women. Differential diagnosis between primary and metastatic neoplasms can be problematic in some cases. The special AT-rich sequence-binding protein 2 (SATB2) is a nuclear matrix-associated protein that is important for growth and development. SATB2 has been shown to...
Purnima Thakur, Vishal Verma, Vikas Fotedar, Kalindi SinghClinical Cancer Investigation Journal 2019 8(2):76-78 A rare case of chronic myeloid leukemia (CML) presenting with priapism is reported in a pediatric patient. CML accounts for around 15% of hematological malignancies. It is still rarer in the pediatric age group. Investigations revealed hyperleukocytosis due to CML. When conservative management failed, priapism was relieved by shunt procedures and the patient was treated with oral chemotherapy....
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