IJMS, Vol. 20, Pages 3130: Chronic Pain: Structural and Functional Changes in Brain Structures and Associated Negative Affective States International Journal of Molecular Sciences doi: 10.3390/ijms20133130 Authors: Seoyon Yang Min Cheol Chang Chronic pain is a condition in which pain progresses from an acute to chronic state and persists beyond the healing process. Chronic pain impairs function and decreases patients’ quality of life. In recent years, efforts have been made...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3129: Magnesium Deficiency Induced Global Transcriptome Change in Citrus sinensis Leaves Revealed by RNA-Seq International Journal of Molecular Sciences doi: 10.3390/ijms20133129 Authors: Yang Zhou Wang Wu Ye Guo Chen Magnesium (Mg) deficiency is one of the major constraining factors that limit the yield and quality of agricultural products. Uniform seedlings of the Citrus sinensis were irrigated with Mg deficient (0 mM MgSO4) and Mg sufficient...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3131: Death-Associated Protein Kinase 1 Phosphorylation in Neuronal Cell Death and Neurodegenerative Disease International Journal of Molecular Sciences doi: 10.3390/ijms20133131 Authors: Nami Kim Dongmei Chen Xiao Zhen Zhou Tae Ho Lee Regulated neuronal cell death plays an essential role in biological processes in normal physiology, including the development of the nervous system. However, the deregulation of neuronal apoptosis by various factors leads...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3127: Norepinephrine Inhibits Synovial Adipose Stem Cell Chondrogenesis via α2a-Adrenoceptor-Mediated ERK1/2 Activation International Journal of Molecular Sciences doi: 10.3390/ijms20133127 Authors: Karima El Bagdadi Frank Zaucke Andrea Meurer Rainer H. Straub Zsuzsa Jenei-Lanzl In recent years, first evidences emerged that sympathetic neurotransmitters influence osteoarthritis (OA) manifestation. Joint-resident stem cells might contribute to cartilage...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3128: Lineage-Specific Evolved MicroRNAs Regulating NB-LRR Defense Genes in Triticeae International Journal of Molecular Sciences doi: 10.3390/ijms20133128 Authors: Zhang Zhang Hao Song Li Li Gao Zheng Li Disease resistance genes encoding proteins with nucleotide binding sites and Leucine-Rich Repeat (NB-LRR) domains include many members involved in the effector-triggered immunity pathway in plants. The transcript levels of these...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3126: Differences in Mutational Profile between Follicular Thyroid Carcinoma and Follicular Thyroid Adenoma Identified Using Next Generation Sequencing International Journal of Molecular Sciences doi: 10.3390/ijms20133126 Authors: Martyna Borowczyk Ewelina Szczepanek-Parulska Szymon Dębicki Bartłomiej Budny Frederik A. Verburg Dorota Filipowicz Barbara Więckowska Małgorzata Janicka-Jedyńska Lidia Gil Katarzyna Ziemnicka Marek Ruchała We...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3124: Genome Wide Association Study of Karnal Bunt Resistance in a Wheat Germplasm Collection from Afghanistan International Journal of Molecular Sciences doi: 10.3390/ijms20133124 Authors: Vikas Gupta Xinyao He Naresh Kumar Guillermo Fuentes-Davila Rajiv K. Sharma Susanne Dreisigacker Philomin Juliana Najibeh Ataei Pawan K. Singh Karnal bunt disease of wheat, caused by the fungus Neovossia indica, is one of the most important challenges to...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3125: Whole Body Vibration-Induced Omental Macrophage Polarization and Fecal Microbiome Modification in a Murine Model International Journal of Molecular Sciences doi: 10.3390/ijms20133125 Authors: Jack C. Yu Vanessa L. Hale Hesam Khodadadi Babak Baban Human nutrient metabolism, developed millions of years ago, is anachronistic. Adaptive features that offered survival advantages are now great liabilities. The current dietary pattern, coupled with massively...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3121: Unveiling the Interplay between the TLR4/MD2 Complex and HSP70 in the Human Cardiovascular System: A Computational Approach International Journal of Molecular Sciences doi: 10.3390/ijms20133121 Authors: Amanda Almeida de Oliveira Josemar Faustino Maria Elena de Lima Ronaldo Menezes Kenia Pedrosa Nunes While precise mechanisms underlying cardiovascular diseases (CVDs) are still not fully understood, previous studies suggest that the innate immune...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3122: Proteomic Analysis of Morphologically Changed Tissues after Prolonged Dexamethasone Treatment International Journal of Molecular Sciences doi: 10.3390/ijms20133122 Authors: Abeer K. Malkawi Afshan Masood Zakia Shinwari Minnie Jacob Hicham Benabdelkamel Goran Matic Falah Almuhanna Majed Dasouki Ayodele A. Alaiya Anas M. Abdel Rahman Prolonged dexamethasone (Dex) administration leads to serious adverse and decrease brain and heart size,...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3118: Comparative Study between Laser Light Stereo-Lithography 3D-Printed and Traditionally Sintered Biphasic Calcium Phosphate Scaffolds by an Integrated Morphological, Morphometric and Mechanical Analysis International Journal of Molecular Sciences doi: 10.3390/ijms20133118 Authors: Carlo Mangano Francesco Mangano Luigi Gobbi Oleg Admakin Satoshi Iketani Alessandra Giuliani In dental districts, successful bone regeneration using biphasic calcium...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3120: MPLs-Pred: Predicting Membrane Protein-Ligand Binding Sites Using Hybrid Sequence-Based Features and Ligand-Specific Models International Journal of Molecular Sciences doi: 10.3390/ijms20133120 Authors: Chang Lu Zhe Liu Enju Zhang Fei He Zhiqiang Ma Han Wang Membrane proteins (MPs) are involved in many essential biomolecule mechanisms as a pivotal factor in enabling the small molecule and signal transport between the two sides of the biological...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3123: Epigenetic Mechanisms in Hirschsprung Disease International Journal of Molecular Sciences doi: 10.3390/ijms20133123 Authors: Ana Torroglosa Leticia Villalba-Benito Berta Luzón-Toro Raquel María Fernández Guillermo Antiñolo Salud Borrego Hirschsprung disease (HSCR, OMIM 142623) is due to a failure of enteric precursor cells derived from neural crest (EPCs) to proliferate, migrate, survive or differentiate during Enteric Nervous System (ENS) formation....
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3119: Isolated Compounds from Turpinia formosana Nakai Induce Ossification International Journal of Molecular Sciences doi: 10.3390/ijms20133119 Authors: Zuha Imtiyaz Yi-Fang Wang Yi-Tzu Lin Hui-Kang Liu Mei-Hsien Lee Bone metabolism is a homeostatic process, imbalance in which leads to the onset of diseases such as osteoporosis and osteopenia. Although several drugs are currently available to treat such conditions, they are associated with severe side...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3116: In Vivo Piggybac-Based Gene Delivery towards Murine Pancreatic Parenchyma Confers Sustained Expression of Gene of Interest International Journal of Molecular Sciences doi: 10.3390/ijms20133116 Authors: Masahiro Sato Emi Inada Issei Saitoh Shingo Nakamura Satoshi Watanabe The pancreas is a glandular organ that functions in the digestive system and endocrine system of vertebrates. The most common disorders involving the pancreas are diabetes, pancreatitis,...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3117: Dual Role of Metallic Trace Elements in Stress Biology—From Negative to Beneficial Impact on Plants International Journal of Molecular Sciences doi: 10.3390/ijms20133117 Authors: Ewa Muszyńska Mateusz Labudda Heavy metals are an interesting group of trace elements (TEs). Some of them are minutely required for normal plant growth and development, while others have unknown biological actions. They may cause injury when they are applied in an elevated concentration,...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3115: The Dualistic Effect of COX-2-Mediated Signaling in Obesity and Insulin Resistance International Journal of Molecular Sciences doi: 10.3390/ijms20133115 Authors: Pei-Chi Chan Min-Tser Liao Po-Shiuan Hsieh Obesity and insulin resistance are two major risk factors for the development of metabolic syndrome, type 2 diabetes and associated cardiovascular diseases (CVDs). Cyclooxygenase (COX), a rate-limiting enzyme responsible for the biosynthesis of prostaglandins...
Wed Jun 26, 2019 03:00
IJMS, Vol. 20, Pages 3114: Molecular Inverse Comorbidity between Alzheimer’s Disease and Lung Cancer: New Insights from Matrix Factorization International Journal of Molecular Sciences doi: 10.3390/ijms20133114 Authors: Alessandro Greco Jon Sanchez Valle Vera Pancaldi Anaïs Baudot Emmanuel Barillot Michele Caselle Alfonso Valencia Andrei Zinovyev Laura Cantini Matrix factorization (MF) is an established paradigm for large-scale biological data analysis with tremendous...
Wed Jun 26, 2019 03:00
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