Τετάρτη 26 Ιουνίου 2019

Phosphorylated STAT3 expression predicts better prognosis in smoldering type of adult T cell leukemia/lymphoma
Abstract Adult T cell leukemia/lymphoma (ATLL) is a mature T cell neoplasm, and is divided into two indolent (smoldering and chronic) and two aggressive (acute and lymphoma) clinical subtypes. Based on previous integrated molecular analyses suggesting the importance of the JAK‐STAT pathway in ATLL, we attempted to clarify the clinicopathological significance of this pathway. Clinical and morphological findings were reviewed in 116 cases with ATLL. The nuclear localizations of phosphorylated STAT3...
Cancer Science
Tue Jun 25, 2019 11:08
Early clinical outcomes of helical Tomotherapy/ intensity modulated proton therapy combination in nasopharynx cancer
Summary This study aimed to evaluate the feasibility of combining helical Tomotherapy (HT) and intensity‐modulated proton therapy (IMPT) in treating the patients with nasopharynx cancer (NPC). From January 2016 till March 2018, 98 patients received definitive radiation therapy (RT) with concurrent chemotherapy (CCRT). Using simultaneous integrated boost and adaptive re‐plan, 3 different dose levels were prescribed: 68.4 Gy in 30 fractions to GTV, 60 Gy in 30 fractions to high‐risk CTV, and 36 Gy...
Cancer Science
Tue Jun 25, 2019 11:08

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