Τετάρτη 26 Ιουνίου 2019

Role of Hyaluronan in Inflammatory Effects on Human Articular Chondrocytes
Abstract Hyaluronan (HA) fragments have been proposed to elicit defensive or pro-inflammatory responses in many cell types. For articular chondrocytes in an inflammatory environment, studies have failed to reach consensus on the endogenous production or effects of added HA fragments. The present study was undertaken to resolve this discrepancy. Cultured primary human articular chondrocytes were exposed to the inflammatory cytokine IL-1β,...
Latest Results for Inflammation
03:00
The Role of Interferon Regulatory Factor 5 in Macrophage Inflammation During Osteoarthritis
Abstract Mounting evidence suggests that aberrant immune responses are involved in the pathogenesis of osteoarthritis (OA). Synovial macrophages are likely involved. In this study, we sought to investigate the role of interferon regulatory factor 5 (IRF5). In vitro M1-polarized macrophages presented significantly higher IRF5 expression than M2-polarized macrophages. Interestingly, IRF5 expression was observed in macrophages from the synovial...
Latest Results for Inflammation
Wed Jun 26, 2019 03:00

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