Researchers suggest a possible cell-based therapy to stimulate lung development in fragile premature infants who suffer from a rare condition called Bronchopulmonary Dysplasia (BPD), which in the most severe cases can lead to lifelong breathing problems and even death. Scientists studied genetic signatures in donated human neonatal lungs by using single-cell RNA sequencing analysis and mouse models of BPD.
A new study finds that the gene FOXA1 overrides normal biology in three different ways to drive prostate cancer. They refer to the three classes as FAST, FURIOUS, and LOUD to reflect their unique features.
How did humans get to be so much fatter than our closest primate relatives, despite sharing 99% of the same DNA? A new study suggests that part of the answer may have to do with an ancient molecular shift in how DNA is packaged inside fat cells, which curbed our body's ability to turn 'bad' white fat into 'good' brown fat.
Researchers have studied which genes are expressed in overactive immune cells in mice with asthma-like inflammation of the airways. Their results suggest that the synthesis and breakdown of fats plays an important part in the process.
Hand hygiene is a critical component of infection prevention in hospitals, but the unintended consequences include water splashing out of a sink to spread contaminants from dirty faucets according to new research.
People who order their Buffalo wings especially spicy and sometimes find them to be too 'hot,' should choose milk to reduce the burn, according to researchers, who also suggest it does not matter if it is whole or skim.
As Asia and Europe battle African swine fever outbreaks, new research shows how farmers' risk attitudes affect the spread of infectious animal diseases and offers a first-of-its kind model for testing disease control and prevention strategies. Getting just 10% of risk tolerant farmers to adopt biosecurity measures resulted in a significant reduction of disease, but keeping the disease under control required at least 40% of risk-takers to change their behaviors.
Women exposed to triclosan are more likely to develop osteoporosis, according to a new study.
A new study that sheds light on how the brain processes language could lead to a better understanding of autism spectrum disorder, schizophrenia and other neurodevelopmental conditions.
Better care and more research into treatments for people experiencing a first manic episode are urgently needed, according to researchers. The study describes patchy and inconsistent care, widespread failure to detect bipolar disorder early enough, and a lack of guidance on how to treat people experiencing mania for the first time.
For the first time, scientists can record cells communicating in real time, opening the floodgates for new developments in cell therapy and other areas within cell biology.
Micronutrient deficiencies, including vitamins B12 and D, as well as folate, iron, zinc and copper, are common in adults at the time of diagnosis with celiac disease. These deficiencies should be addressed at that time, according to a new study.
Researchers have discovered a secret sauce in the brain's vascular system that preserves the neurons needed to keep dementia and other diseases at bay.
In a study using brain tissue from deceased human donors, researchers say they found new evidence that schizophrenia can be marked by the buildup of abnormal proteins similar to those found in the brains of people with such neurodegenerative disorders as Alzheimer's or Huntington's diseases.
Time-saving method makes it possible to profile gene regulation in tens of thousands of individual human cells in a single day. Approach combines microfluidics and novel software to scale up single-cell ATAC-seq, which identifies parts of the tightly packaged genome that are more open and accessible to regulatory proteins. Profiling individual cells can clarify how genes function - in which specific cell types, at what time - and whether they play a role in disease.
Non-classical monocytes were long thought to pl
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