Association of gastro-oesophageal reflux disease and quality of life in patients with chronic rhinosinusitis

xlomafota13 shared this article with you from Inoreader Association of gastro-oesophageal reflux disease and quality of life in patients with chronic rhinosinusitis Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Oct;41(5):450-460. doi: 10.14639/0392-100X-N1491. ABSTRACT OBJECTIVE: We determined the influence of gastro-oesophageal reflux disease (GERD) on quality of life (QOL) before and after functional-endoscopic-sinus-surgery (FESS) for chronic rhinosinusitis (CRS). METHODS: Medically-recalcitrant CRS patients were recruited prior to FESS. GERD was diagnosed endoscopically. QOL was compared between patients with vs without GERD at base line and one-year post-FESS. RESULTS: Of 187 CRS patients receiving FESS, 40 had GERD. Pre-operative QOL was significantly worse in CRS patients with vs without GERD. Pre-operative GERD health-related QOL (GERD-HRQL) and reflux symptom index (RSI) scores were both correlated with pre-operative SNOT-22 scores. Compared with non-GERD CRS patients, GERD patients demonstrated larger SNOT-22 improvements after FESS, such that post-operative SNOT-22 values were no longer significantly different between GERD and non-GERD groups. However, post-FESS, in patients with CRS without nasal polyps (unlike those with nasal polyps), the GERD (vs non-GERD) group suffered from greater sleep dysfunction and otologic/facial symptoms. CONCLUSIONS: Compared to CRS patients without GERD, those with GERD experienced poorer pre-operative QOL and greater QOL improvement after FESS. PMID:34734581 | DOI:10.14639/0392-100X-N1491 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.