Vaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c MiceVaccines, Vol. 7, Pages 162: Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice Vaccines doi: 10.3390/vaccines7040162 Authors: Rory Cristiane Fortes De Brito Jamille Mirelle de Oliveira Cardoso Levi...
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International Journal of Molecular Sciences IJMS, Vol. 20, Pages 5358: Fatty Acid-Binding Protein...
International Journal of Molecular SciencesIJMS, Vol. 20, Pages 5358: Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP+-Induced Mitochondrial Dysfunction in Cultured Dopaminergic NeuronsIJMS, Vol. 20, Pages 5358: Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP+-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons International Journal of Molecular Sciences doi: 10.3390/ijms20215358 Authors: Ichiro Kawahata Luc Bousset Ronald Melki Kohji...
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Antibiotics, Vol. 8, Pages 200: The Association between Changes in External Environment Caused by Migration and Inappropriate Antibiotic Use Behaviors among Chinese University Students: A Cross-Sectional StudyAntibiotics, Vol. 8, Pages 200: The Association between Changes in External Environment Caused by Migration and Inappropriate Antibiotic Use Behaviors among Chinese University Students: A Cross-Sectional Study Antibiotics doi: 10.3390/antibiotics8040200 Authors: Jingjing Lu Xiaomin Wang Leesa...
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The Journal of Antibiotics - Winners of the 2018 JA Ōmura Awards for excellenceThe Journal of Antibiotics, Published online: 28 October 2019; doi:10.1038/s41429-019-0233-5Winners of the 2018 JA Ōmura Awards for excellenceThe Journal of Antibiotics - Issue - nature.com science feeds02:00Winners of the 2018 JA Ōmura Awards for excellenceThe Journal of Antibiotics - Issue - nature.com science feeds01:05Mark above section as read Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry...
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Journal of Biophotonics,Photobiomodulation Therapy for Repeated Closed Head Injury in RatsAbstract Repeated traumatic brain injury, leads to cumulative neuronal injury and neurological impairments. There are currently no effective treatments to prevent these consequences. Growing interest is building in the use of transcranial photobiomodulation (PBM) therapy to treat TBI. Here, we examined PBM in a repeated closed head injury (rCHI) rat model. Rats were administered a total of three closed head...
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Journal of Trauma and Acute Care Surgery - Influence of prehospital physician presence on survival after severe trauma: Systematic review and meta-analysisBACKGROUND As trauma is one of the leading causes of death worldwide, there is great potential for reducing mortality in trauma patients. However, there is continuing controversy over the benefit of deploying emergency medical systems (EMS) physicians in the prehospital setting. The objective of this systematic review and meta-analysis is to assess...
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SurgRob,Da Vinci proceduresSome recent clinical outcome numbers for the da Vinci: "In May of this year, a large scale, real-world comparative study using the National Cancer Database was published in the journal, Colorectal Disease. The analysis, led by Dr. Ravi Kiran from NewYork-Presbyterian/Columbia University Medical Center, compared the results of over 41,000 patients from between 2010 and 2015 by surgical approach. The National Cancer Database captures data from over 1,500 cancer-accredited...
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Journal of Neuroendocrinology,The role of oxytocin in regulation of appetitive behavior, body weight and glucose homeostasisAbstract Obesity and its associated complications have reached epidemic proportions in the US and worldwide, highlighting the need for new and more effective treatments. While the neuropeptide oxytocin (OXT) is well recognized for its peripheral effects on reproductive behavior, release of OXT from somatodendrites and axonal terminals within the central nervous system (CNS)...
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Latest Results for Journal of Microbiology,Propionate, together with triple antibiotics, inhibits the growth of EnterococciAbstract Enterococci are Gram-positive facultative anaerobic bacteria that colonize the oral cavity and gastrointestinal tract. Enterococcal infections, mainly caused by Enterococcus faecalis and Enterococcus faecium, include apical periodontitis, endocarditis, and bloodstream infections. Recently, vancomycinresistant Enterococci are considered major pathogens that are common...
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Journal of Biophotonics,Photobiomodulation Therapy for Repeated Closed Head Injury in RatsAbstract Repeated traumatic brain injury, leads to cumulative neuronal injury and neurological impairments. There are currently no effective treatments to prevent these consequences. Growing interest is building in the use of transcranial photobiomodulation (PBM) therapy to treat TBI. Here, we examined PBM in a repeated closed head injury (rCHI) rat model. Rats were administered a total of three closed head...
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RSC - Chem. Commun. Magnetism in Ln Molecular Systems with 4f/valence-shell interplay (FV-Magnetism)Chem. Commun., 2019, Accepted ManuscriptDOI: 10.1039/C9CC06913E, CommunicationVasilii Dubrovin, Alexey A Popov, Stanislav AvdoshenkoThe hunt for the high-performance single-molecule magnets (SMM) revealed that atomic and molecular lanthanide systems combining 4f-shell and valence magnetism (FV-magnetism) may show magnetic bistability up to unexpectedly high temperatures....The content of this RSS...
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Latest Results for Acta Neurochirurgica,Prognostic performance of computerized tomography scoring systems in civilian penetrating traumatic brain injury: an observational studyAbstract Background The prognosis of penetrating traumatic brain injury (pTBI) is poor yet highly variable. Current computerized tomography (CT) severity scores are commonly not used for pTBI prognostication but may provide important clinical information in these cohorts. Methods All consecutive pTBI patients from two large...
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Vascular reactivity to mental stress is associated with poor cardiovascular disease outcomes in females following acute coronary syndromeBackground: We aimed to test the hypothesis that peripheral endothelial dysfunction induced by mental stress may predict cardiovascular events after acute coronary syndrome beyond traditional cardiovascular disease risk factors. Methods: This was a prospective study in which 417 patients who had acute coronary syndrome were enrolled in two sites at the US and Qatar....
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Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza...Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017...
Sun Oct 27, 2019 12:11
Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017 Viruses doi: 10.3390/v11110990 Authors: Yassmin Moatasim Ahmed Kandeil Basma Emad Aboulhoda Rabeh El-Shesheny...
Sun Oct 27, 2019 12:06
Journal of Clinical MedicineJCM, Vol. 8, Pages 1801: A Cross-Sectional Study of Hyponatremia Associated with Acute Central Nervous System InfectionsJCM, Vol. 8, Pages 1801: A Cross-Sectional Study of Hyponatremia Associated with Acute Central Nervous System Infections Journal of Clinical Medicine doi: 10.3390/jcm8111801 Authors: Andy K.H. Lim Sahira Paramaswaran Lucy J. Jellie Ralph K. Junckerstorff Hyponatremia can occur with central nervous system (CNS) infections, but the frequency and severity...
Sun Oct 27, 2019 12:06
Antioxidants, Vol. 8, Pages 513: Modulation of Reactive Oxygen Species in Health and DiseaseAntioxidants, Vol. 8, Pages 513: Modulation of Reactive Oxygen Species in Health and Disease Antioxidants doi: 10.3390/antiox8110513 Authors: Solomon Habtemariam In diverse living organisms, signaling within the cell, chemical communication between cells or simply the fate of cells to survive or die is largely dependent on the intricate balance of control mechanisms related to reactive oxygen species (ROS)[...]AntioxidantsSat...
Sun Oct 27, 2019 12:05
Latest Results for Acta Analytica,A Defense of Free-Roaming Cats from a Hedonist Account of Feline Well-beingAbstract There is a widespread belief that for their own safety and for the protection of wildlife, cats should be permanently kept indoors. Against this view, I argue that cat guardians have a duty to provide their feline companions with outdoor access. The argument is based on a sophisticated hedonistic account of animal well-being that acknowledges that the performance of species-normal...
Sun Oct 27, 2019 12:02
Biomedicine & Pharmacotherapy,Icariin modulates carrageenan-induced acute inflammation through HO-1/Nrf2 and NF-kB signaling pathwaysPublication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Nagla A. El-Shitany, Basma G. EidAbstractCellular inflammation has been recognized as the leading factor in numerous diseases, causing either cell death, organ-specific damage, or genesis of different cancers. Icariin, a flavonol glucoside, extracted from Herba Epimedii,...
Sun Oct 27, 2019 12:00
Delay of Surgery for DCIS Ups Risk for Invasive Breast CancerEach month delay increases risk for invasive cancer by 1 percent (Source: The Doctors Lounge - Oncology)The Doctors Lounge - Oncology19hMark above section as read The Journal of PhysiologyLocation, location, location: Lessons from airway epithelial anion channelsThe Journal of Physiology20hRegional activation in the human longissimus thoracis pars lumborum muscleKey points •Longissimus activity in the lumbar region was measured using indwelling...
Sun Oct 27, 2019 11:56
ScienceDirect Publication Sleep Medicine,Utility of the pictorial Epworth sleepiness scale in the adult Down syndrome populationPublication date: Available online 25 October 2019Source: Sleep MedicineAuthor(s): Elizabeth Hill, Donna Fairley, Ewan McConnell, Ian Morrison, Marta Celmina, Serafeim – Chrysovalantis Kotoulas, Renata L. RihaAbstractObjective/BackgroundThe utility of the pictorial Epworth sleepiness scale (pESS) has been assessed by only a few studies in a clinical population. Some of...
Sun Oct 27, 2019 11:55
Syphilis, congenitalSyphilis, congenital: Infection of a fetus or newborn with syphilis. Syphilis in a fetus can cause deformity, particularly of the long bones, or death. Syphilis infection acquired at birth is also dangerous. See also TORCH infection.MedTerms (TM) is the Medical Dictionary of MedicineNet.com.We Bring Doctors' Knowledge To YouMedTerms Word of the Day4hMark above section as read Movement DisordersDriving genotype treatment options down the right path(way)Movement Disorders12hMark...
Sun Oct 27, 2019 11:54
Latest Results for Education and Information TechnologiesE-learning readiness of universities in Nigeria- what are the opinions of the academic staff of Nigeria's premier university?Abstract This paper examined the opinions of academic staff of the University of Ibadan Nigeria regarding the preparedness of stakeholders of e-learning in Nigeria for fruitful e-learning experience and action in Nigerian universities. Data was collected from 240 lecturers using a questionnaire. The lecturers considered...
Sun Oct 27, 2019 11:53
Pediatric Metabolic and Bariatric Surgery: Evidence, Barriers, and Best PracticesSevere obesity among youth is an "epidemic within an epidemic" and portends a shortened life expectancy for today's children compared with those of their parents' generation. Severe obesity has outpaced less severe forms of childhood obesity in prevalence, and it disproportionately affects adolescents. Emerging evidence has linked severe obesity to the development and progression of multiple comorbid states, including...
Sun Oct 27, 2019 11:52
Journal of Pediatric Surgery,Learning Health Systems and the Future of Clinical ResearchPediatric surgeons are collectively passionate about prioritizing the healthcare needs of children. We contend that this passion is deeply ingrained in how we drive clinical care and influence scientific discovery. Thus, the future of clinical research in our field will be deeply embedded in our history as a "patient-centric" profession. Service to pediatric patients requires an understanding of their needs and...
Sun Oct 27, 2019 11:51
Hindawi Publishing Corporation,Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical StressBackground. Mechanical stress-induced cardiac remodeling that results in heart failure is characterized by transcriptional reprogramming of gene expression. However, a systematic study of genomic changes involved in this process has not been performed...
Sun Oct 27, 2019 11:49
Gastrointestinal Endoscopy,Discrepancy between self-reported and actual colonoscopy polypectomy practices for the removal of small polypsCold snare polypectomy (CSP) is associated with higher complete resection rates when compared with cold biopsy forceps (CBF) for the removal of small polyps (4-9 mm). This study aimed to evaluate self-reported polypectomy preferences and actual practice patterns among endoscopists at an academic center and to identify factors associated with the use of CSP for...
Sun Oct 27, 2019 11:48
American Journal of Medical Genetics Part A,Behavioral characterization of dup15q syndrome: Toward meaningful endpoints for clinical trialsAbstract Duplication of 15q11.2‐q13.1 (dup15q syndrome) is one of the most common copy number variations associated with autism spectrum disorders (ASD) and intellectual disability (ID). As with many neurogenetic conditions, accurate behavioral assessment is challenging due to the level of impairment and heterogeneity across individuals. Large‐scale phenotyping...
Sun Oct 27, 2019 11:48
Psycho-Oncology,Stigma and its correlates in people living with lung cancer: A cross‐sectional study from ChinaAbstract Objectives This study aimed to examine the level of stigma and identify the correlates of stigma among lung cancer patients in China. Methods In total, 283 lung cancer patients were recruited from a tertiary cancer center in China by the convenience sampling method and completed a demographic, disease‐related information and situational characteristics questionnaire and self‐reported...
Sun Oct 27, 2019 11:46
Psycho-Oncology,Stigma and its correlates in people living with lung cancer: A cross‐sectional study from ChinaAbstract Objectives This study aimed to examine the level of stigma and identify the correlates of stigma among lung cancer patients in China. Methods In total, 283 lung cancer patients were recruited from a tertiary cancer center in China by the convenience sampling method and completed a demographic, disease‐related information and situational characteristics questionnaire and self‐reported...
Sun Oct 27, 2019 11:45
The Journal of Physiology,Regional activation in the human longissimus thoracis pars lumborum muscleKey points •Longissimus activity in the lumbar region was measured using indwelling electromyography to characterize the territory of its motor units. •The distribution of motor units in the longissimus pars lumborum muscle was mainly grouped into two distinct regions. •Regional activation of the longissimus pars lumborum was also observed during functional tasks involving trunk movements. •The regional...
Sun Oct 27, 2019 11:44
Clinical ImmunologyImmunomodulatory receptors are differentially expressed in B and T cell subsets relevant to autoimmune diseasePublication date: Available online 25 October 2019Source: Clinical ImmunologyAuthor(s): Katherine A. Murphy, Kartik Bhamidiphati, Samuel J.S. Rubin, Lucas Kipp, William H. Robinson, Tobias V. LanzAbstractInhibitory cell-surface receptors on lymphocytes, often called immune checkpoints, are powerful targets for cancer therapy. Despite their direct involvement in autoimmune...
Sun Oct 27, 2019 11:43
Journal of NeuroEngineering and Rehabilitation - Cervical trans-spinal direct current stimulation: a modelling-experimental approachTrans-spinal direct current stimulation (tsDCS) is a non-invasive technique with promising neuromodulatory effects on spinal cord (SC) circuitry. Computational studies are essential to guide effective tsDCS pr...Journal of NeuroEngineering and Rehabilitation - Latest Articles17hMark above section as read Journal of Cancer EducationAdvance Care Planning Conversations...
Sun Oct 27, 2019 11:42
Latest Results for Acta Neuropathologica Communications, Dynein activating adaptor BICD2 controls...
Latest Results for Acta Neuropathologica Communications,Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivoAbstract For the proper organization of the six-layered mammalian neocortex it is required that neurons migrate radially from their place of birth towards their designated destination. The molecular machinery underlying this neuronal migration is still poorly understood. The dynein-adaptor protein BICD2 is associated with a spectrum of human neurological...
Sun Oct 27, 2019 11:41
The Laryngoscope,The prevalence of cognitive impairment in laryngology treatment–seeking patientsObjectives/Hypothesis The incidence of cognitive impairment (CI) in the elderly general population is 10% to 20%. The incidence of CI in the elderly laryngology treatment–seeking population is unknown, and CI may impact decision making for elective medical/surgical treatment and negatively impact the outcome of voice/swallowing therapy. We sought to determine the prevalence of CI in elderly patients...
Sun Oct 27, 2019 11:40
Cancer Medicine,Real‐world health utility scores and toxicities to tyrosine kinase inhibitors in epidermal growth factor receptor mutated advanced non‐small cell lung cancerReal‐world health utility scores (HUS) in epidermal growth factor receptor mutations (EGFRm) non‐small cell lung cancer outpatients were similar between those treated by first‐ and second‐line tyrosine kinase inhibitors, which were superior to chemotherapy. Treatment‐associated toxicities corresponded to HUS of treatment groups....
Sun Oct 27, 2019 11:39
Latest Results for Rheumatology and Therapy,Risk of Potential Glucocorticoid-Related Adverse Events in Patients with Giant Cell Arteritis: Results from a USA-Based Electronic Health Records DatabaseAbstract Introduction Oral glucocorticoids (GC) have been the mainstay of treatment for giant cell arteritis (GCA). We estimated the risk and dose–effect relationship of potential GC-related adverse events (AEs) in patients with GCA. Methods This retrospective, observational cohort study utilized data...
Sun Oct 27, 2019 11:38
Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza...Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017...
Sun Oct 27, 2019 12:11
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